BS6699

antibody from Bioworld Technology, Inc
Targeting: PPA1 IOPPP, PP, PP1, Ppase, SID6-8061
Provider product page for BS6699
Western blot
Immunohistochemistry

Antibody data

Product number
BS6699 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PPA1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PPA1.
Description
PPA1 (Pyrophosphate phospho-hydrolase 1), also known as IOPPP (inorganic pyrophosphatase), PP1, PP or PPase, belongs to the PPase family of inorganic pyrophosphatases. Inorganic pyrophosphatases catalyze the intracellular conversion of pyrophosphate to inorganic phosphate, a key reaction for phosphate metabolism in cells. PPA1 is a ubiquitously expressed protein that localizes to the cytoplasm and is required for cell growth. It exists as a homodimer exhibiting magnesium dependent activity. The binding of two magnesium ions is required to stimulate PPA1 activity; however, both subunits in the homodimer are capable of binding four magnesium ions. The additional ions are useful in forming complexes with substrates and products. In addition, the activity of PPA1 can be inhibited by calcium.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PPA1 protein structure - BS6699 shown in red.