11-12004

antibody from ABEOMICS Inc.
Targeting: KLF4 EZF, GKLF
Provider product page for 11-12004

Antibody data

Product number
11-12004 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-KLF4 Antibody
Antibody type
Polyclonal
Description
Kruppel like factor 4 (KLF4) which are also called as gun enriched kruppel like factors (GKLF) is a member of SP/KLF family of zinc transcription factors that are involved in numerous important cellular processes, such as, proliferation, inflammation, apoptosis and somatic cell reprogramming. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmented gene. This protein is found to inhibit cell proliferation by functioning as a cell cycle checkpoint protein that leads to activation of transcription of the cyclin-dependent kinase inhibitor. Clinically KLF4 plays a role in the pathogenesis of esophageal cancer and malaria. It has five isoform that are produced by alternate splicing. Expression of KLF4 is highly enriched in the post replicative epithelial cells of the intestine, skin and thymus.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant KLF4 p
rotein (amino acids 1-300) was used
as the immunogen for this antibody
.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
KLF4 protein structure - 11-12004 shown in red.