Antibody data
- Antibody Data
- Antigen structure
- References [49]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 10593-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10593-1-AP, RRID:AB_2182736
- Product name
- CD138/Syndecan-1 antibody
- Antibody type
- Polyclonal
- Description
- CD138/Syndecan-1 antibody (Cat. #10593-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.
Mechanical Strain-Programmed SDC1(+) Sheath Fibroblasts Trigger CXCR4(hi) Neutrophil-Mediated Enthesitis in Ankylosing Spondylitis.
Effect of estradiol valerate on humoral immune function in BALB/c mice after total hysterectomy.
Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritis.
Targeting the origins of multiple myeloma along hematopoietic stem cell lymphoid lineage differentiation.
The role of Collagen Tissue Scaffolds in 3D Endometrial-like Culture Systems: Important Contributions to Cell Invasion and Cell Topography.
Effect of high-fat diet on IgA(+) cells and BAFF/APRIL in small intestinal villous lamina propria of mice.
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization.
Efficacy and tolerability of neoadjuvant therapy with Talimogene laherparepvec in cutaneous basal cell carcinoma: a phase II trial (NeoBCC trial).
Hydrogen sulfide alleviates endothelial glycocalyx damage and promotes placental angiogenesis in rats exposed to cigarette smoke.
Tetraspanin CD81 serves as a functional entry factor for porcine circovirus type 2 infection.
Serum-soluble SDC1 in septic patients is rich in heparan sulfate, which affects the ELISA quantification values.
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
Multidimensional role of adapalene in regulating cell death in multiple myeloma.
Chronic endometritis and the endometrial microbiota: implications for reproductive success in patients with recurrent implantation failure.
IL-34 and its receptors as predictors of brain metastasis and prognosis in lung adenocarcinoma: Unveiling insights through bioinformatic and immunohistochemical investigations.
MZ1, a BRD4 inhibitor, exerted its anti-cancer effects by suppressing SDC1 in glioblastoma.
SDC1-TGM2-FLOT1-BHMT complex determines radiosensitivity of glioblastoma by influencing the fusion of autophagosomes with lysosomes.
SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
miR-19a-3p affected ox-LDL-induced SDC-1/TGF-β1/Smad3 pathway in atherosclerosis.
LHPP Inhibits the Viability, Migration, and Proliferation of PDAC Cells and Significantly Affects the Expression of SDC1 and S100p.
Interleukin-32γ promotes macrophage-mediated chemoresistance by inducing CSF1-dependent M2 macrophage polarization in multiple myeloma.
Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.
Development and Validation of a Prognostic Classifier Based on Lipid Metabolism-Related Genes for Breast Cancer.
SB431542 alleviates lupus nephritis by regulating B cells and inhibiting the TLR9/TGFβ1/PDGFB signaling.
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma.
Tumor-reactive antibodies evolve from non-binding and autoreactive precursors.
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
The association of telomere maintenance and TERT expression with susceptibility to human papillomavirus infection in cervical epithelium.
Transcriptome analysis reveals transforming growth factor-β1 prevents extracellular matrix degradation and cell adhesion during the follicular-luteal transition in cows.
Aurka loss in CD19(+) B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Sclerosing mucoepidermoid carcinoma of the salivary glands: report of three cases with special concern to the counterpart accompanied by eosinophilia.
Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.
miR-21 antagonism abrogates Th17 tumor promoting functions in multiple myeloma.
Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma.
PLP2 Expression as a Prognostic and Therapeutic Indicator in High-Risk Multiple Myeloma.
The cancer cell glycocalyx proteoglycan Glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.
Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus.
CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma.
IL-33 induces production of autoantibody against autologous respiratory epithelial cells: a potential mechanism for the pathogenesis of COPD.
Blockade of deubiquitinase USP7 overcomes bortezomib resistance by suppressing NF-κB signaling pathway in multiple myeloma.
Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Reduced APRIL expression induces cellular senescence via a HSPG-dependent pathway.
Gong Q, Zhao W, Wang T, Pan Y, Cui C, Qu Y, Zhou X
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SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.
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Gut 2026 Feb 10;
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Mechanical Strain-Programmed SDC1(+) Sheath Fibroblasts Trigger CXCR4(hi) Neutrophil-Mediated Enthesitis in Ankylosing Spondylitis.
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THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
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Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
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Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells.
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Oncotarget 2016 Nov 8;7(45):73497-73508
Oncotarget 2016 Nov 8;7(45):73497-73508
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G
Journal of virology 2016 Nov 1;90(21):9632-9643
Journal of virology 2016 Nov 1;90(21):9632-9643
Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Wang X, Zuo D, Chen Y, Li W, Liu R, He Y, Ren L, Zhou L, Deng T, Wang X, Ying G, Ba Y
British journal of cancer 2014 Nov 11;111(10):1965-76
British journal of cancer 2014 Nov 11;111(10):1965-76
Reduced APRIL expression induces cellular senescence via a HSPG-dependent pathway.
Ding W, Ju S, Jiang S, Zhu L, Wang Y, Wang H
Pathology oncology research : POR 2009 Dec;15(4):693-701
Pathology oncology research : POR 2009 Dec;15(4):693-701
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 10593-1-AP(SDC1,CD138 antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 10593-1-AP(SDC1,CD138 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CD138/Syndecan-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD138/Syndecan-1. This antibody recognizes human,mouse,rat antigen. The CD138/Syndecan-1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.