Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12262-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12262-1-AP, RRID:AB_2100540
- Product name
- ETFA antibody
- Antibody type
- Polyclonal
- Description
- ETFA antibody (Cat. #12262-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
A pomalidomide-based gefitinib PROTAC degrader effectively inhibits lung cancer progression in EGFR-TKIs-acquired resistant models by targeting EGFR degradation and ETFA-mediated ATP generation.
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Pomalidomide sensitizes lung cancer cells to TRAIL/CDDP-induced apoptosis via directly targeting electron transfer flavoprotein alpha subunit.
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Global expression study in colorectal cancer on proteins with alkaline isoelectric point by two-dimensional difference gel electrophoresis.
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe.
Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase I inhibitor.
Kiermayer C, Erdelen R, Schriever SC, Böhm R, Prehn C, Artati A, Kleinert M, Miller M, Dyar KA, Schmid RM, Pfluger PT, Adamski J, Brielmeier M
Redox biology 2026 Jun;93:104165
Redox biology 2026 Jun;93:104165
A pomalidomide-based gefitinib PROTAC degrader effectively inhibits lung cancer progression in EGFR-TKIs-acquired resistant models by targeting EGFR degradation and ETFA-mediated ATP generation.
Li L, Li Y, Ma X, Li P, Zeng S, Jiang F, Zhang G
Bioorganic chemistry 2025 Sep;164:108864
Bioorganic chemistry 2025 Sep;164:108864
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Guo W, Zhang C, Zhou Q, Chen T, Xu X, Zhang J, Yu X, Wu H, Zhang X, Ma L, Qian K, Klionsky DJ, Kang R, Kroemer G, Yu Y, Tang D, Wang J
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Pomalidomide sensitizes lung cancer cells to TRAIL/CDDP-induced apoptosis via directly targeting electron transfer flavoprotein alpha subunit.
Li L, Huang Z, Huang Y, Li Y, Ma X, Li P, Du W, Wang H, Zhao Y, Zeng S, Peng Y, Zhang G
Bioorganic chemistry 2024 Dec;153:107815
Bioorganic chemistry 2024 Dec;153:107815
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6
Molecular cell 2022 May 19;82(10):1821-1835.e6
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Peng MZ, Shao YX, Li XZ, Zhang KD, Cai YN, Lin YT, Jiang MY, Liu ZC, Su XY, Zhang W, Jiang XL, Liu L
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
Global expression study in colorectal cancer on proteins with alkaline isoelectric point by two-dimensional difference gel electrophoresis.
Muto T, Taniguchi H, Kushima R, Tsuda H, Yonemori H, Chen C, Sugihara Y, Sakamoto K, Kobori Y, Palmer H, Nakamura Y, Tomonaga T, Tanaka H, Mizushima H, Fujita S, Kondo T
Journal of proteomics 2011 May 16;74(6):858-73
Journal of proteomics 2011 May 16;74(6):858-73
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe.
Singaravelu R, Blais DR, McKay CS, Pezacki JP
Proteome science 2010 Feb 4;8:5
Proteome science 2010 Feb 4;8:5
Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase I inhibitor.
Han B, Stockwin LH, Hancock C, Yu SX, Hollingshead MG, Newton DL
Journal of proteome research 2010 Aug 6;9(8):4016-27
Journal of proteome research 2010 Aug 6;9(8):4016-27
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 12262-1-AP(ETFA antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PNRC2 antibody 12262-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 12262-1-AP(ETFA antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue