Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations [0]
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- Product number
- 27722-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ABCG5 antibody
- Antibody type
- Polyclonal
- Description
- ABCG5 antibody (Cat. #27722-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Polymethoxyflavones in citrus extract has a beneficial effect on hypercholesterolemia rats by promoting liver cholesterol metabolism.
Cholesterol uptake in the intestine is regulated by the LASP1-AKT-NPC1L1 signaling pathway.
Fisetin, a dietary flavonoid, promotes transintestinal cholesterol excretion through the activation of PPARδ.
Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis.
Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.
Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice.
Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.
Preparation of microgel co-loaded with nuciferine and epigallocatechin-3-gallate for the regulation of lipid metabolism.
Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways.
Long Noncoding RNA lncRHL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis.
Di(2-ethylhexyl) phthalate disturbs cholesterol metabolism through oxidative stress in rat liver.
Alisol B 23-acetate adjusts bile acid metabolisim via hepatic FXR-BSEP signaling activation to alleviate atherosclerosis.
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway.
Astragalus Polysaccharides Ameliorate Diet-Induced Gallstone Formation by Modulating Synthesis of Bile Acids and the Gut Microbiota.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis.
Resveratrol enhances trans-intestinal cholesterol excretion through selective activation of intestinal liver X receptor alpha.
Dietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats.
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Ezetimibe promotes CYP7A1 and modulates PPARs as a compensatory mechanism in LDL receptor-deficient hamsters.
Protective effects of L-theanine on rats with dextran sulfate sodium-induced inflammatory bowel disease.
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα.
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Du Y, Su J, Yan M, Wang Q, Wang T, Gao S, Tian Y, Wang Y, Chen S, Lv G, Yu J
Journal of ethnopharmacology 2024 Mar 25;322:117644
Journal of ethnopharmacology 2024 Mar 25;322:117644
Cholesterol uptake in the intestine is regulated by the LASP1-AKT-NPC1L1 signaling pathway.
Butt E, Günder T, Stürzebecher P, Kowalski I, Schneider P, Buschmann N, Schäfer S, Bender A, Hermanns HM, Zernecke A
American journal of physiology. Gastrointestinal and liver physiology 2024 Jul 1;327(1):G25-G35
American journal of physiology. Gastrointestinal and liver physiology 2024 Jul 1;327(1):G25-G35
Fisetin, a dietary flavonoid, promotes transintestinal cholesterol excretion through the activation of PPARδ.
Guo Y, Liu B, Geng Y, Chen K, Li J, Yin X, Zhang S
Food research international (Ottawa, Ont.) 2024 Jan;175:113783
Food research international (Ottawa, Ont.) 2024 Jan;175:113783
Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis.
Meng C, Zhou L, Huang L, Gu Q, Du X, Wang C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155271
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155271
Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.
Huang D, Shen S, Zhuang Q, Ye X, Qian Y, Dong Z, Wan X
Chinese medicine 2024 Jan 24;19(1):16
Chinese medicine 2024 Jan 24;19(1):16
Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice.
Li Z, He M, Chen G, Worgall TS, Jiang XC
bioRxiv : the preprint server for biology 2023 Feb 7;
bioRxiv : the preprint server for biology 2023 Feb 7;
Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.
Zhuang Q, Cheng J, Xia J, Ning M, Wu S, Shen S, Shi Y, Huang D, Dong Z, Wan X
Frontiers in medicine 2022;9:818144
Frontiers in medicine 2022;9:818144
Preparation of microgel co-loaded with nuciferine and epigallocatechin-3-gallate for the regulation of lipid metabolism.
Zhu S, Xu W, Liu J, Guan F, Xu A, Zhao J, Ge J
Frontiers in nutrition 2022;9:1069797
Frontiers in nutrition 2022;9:1069797
Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways.
Yuefeng Y, Zhiqi L, Yi C, Keyu Z, Heng W, Yuying W, Ningjian W, Yuetian Y, Xinjie G, Yihao Z, Yingli L, Fangzhen X
International journal of endocrinology 2022;2022:7989751
International journal of endocrinology 2022;2022:7989751
Long Noncoding RNA lncRHL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis.
Shen X, Zhang Y, Ji X, Li B, Wang Y, Huang Y, Zhang X, Yu J, Zou R, Qin D, Zhou H, Wang Q, Li JZ
Diabetes 2022 Sep 1;71(9):1915-1928
Diabetes 2022 Sep 1;71(9):1915-1928
Di(2-ethylhexyl) phthalate disturbs cholesterol metabolism through oxidative stress in rat liver.
Li G, Zhao CY, Wu Q, Kang Z, Zhang JT, Guan SY, Jin HW, Zhang YB, Na XL
Environmental toxicology and pharmacology 2022 Oct;95:103958
Environmental toxicology and pharmacology 2022 Oct;95:103958
Alisol B 23-acetate adjusts bile acid metabolisim via hepatic FXR-BSEP signaling activation to alleviate atherosclerosis.
Fu Y, Feng H, Ding X, Meng QH, Zhang SR, Li J, Chao Y, Ji TT, Bi YH, Zhang WW, Chen Q, Zhang YH, Feng YL, Bian HM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154120
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154120
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Wang JQ, Li LL, Hu A, Deng G, Wei J, Li YF, Liu YB, Lu XY, Qiu ZP, Shi XJ, Zhao X, Luo J, Song BL
Nature 2022 Aug;608(7922):413-420
Nature 2022 Aug;608(7922):413-420
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Li L, Zhong S, Li R, Liang N, Zhang L, Xia S, Xu X, Chen X, Chen S, Tao Y, Yin H
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway.
Zhao F, Ma S, Zhou Y, Wei B, Hao Z, Cui X, Xing L, Liu G, Jin L, Ma T, Shi L
International journal of biological sciences 2021;17(15):4459-4473
International journal of biological sciences 2021;17(15):4459-4473
Astragalus Polysaccharides Ameliorate Diet-Induced Gallstone Formation by Modulating Synthesis of Bile Acids and the Gut Microbiota.
Zhuang Q, Ye X, Shen S, Cheng J, Shi Y, Wu S, Xia J, Ning M, Dong Z, Wan X
Frontiers in pharmacology 2021;12:701003
Frontiers in pharmacology 2021;12:701003
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ
Nutrients 2021 Sep 10;13(9)
Nutrients 2021 Sep 10;13(9)
HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis.
Zhang Z, Wen H, Peng B, Weng J, Zeng F
Molecular therapy. Nucleic acids 2021 Jun 4;24:711-727
Molecular therapy. Nucleic acids 2021 Jun 4;24:711-727
Resveratrol enhances trans-intestinal cholesterol excretion through selective activation of intestinal liver X receptor alpha.
Pang J, Xu H, Wang X, Chen X, Li Q, Liu Q, You Y, Zhang H, Xu Z, Zhao Y, Zhang Y, Yang Y, Ling W
Biochemical pharmacology 2021 Apr;186:114481
Biochemical pharmacology 2021 Apr;186:114481
Dietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats.
Li S, Xu S, Zhao Y, Wang H, Feng J
Nutrients 2020 May 13;12(5)
Nutrients 2020 May 13;12(5)
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα.
Li T, Hu SM, Pang XY, Wang JF, Yin JY, Li FH, Wang J, Yang XQ, Xia B, Liu YH, Song WG, Guo SD
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Journal of cellular and molecular medicine 2020 Mar;24(6):3384-3398
Ezetimibe promotes CYP7A1 and modulates PPARs as a compensatory mechanism in LDL receptor-deficient hamsters.
Xia B, Lin P, Ji Y, Yin J, Wang J, Yang X, Li T, Yang Z, Li F, Guo S
Lipids in health and disease 2020 Feb 8;19(1):24
Lipids in health and disease 2020 Feb 8;19(1):24
Protective effects of L-theanine on rats with dextran sulfate sodium-induced inflammatory bowel disease.
Chen L, Xiao WJ, Yan QX, Gong ZH, Zhang S, Zeng L, Yang M, Zhou YH
Archives of pharmacal research 2020 Aug;43(8):821-862
Archives of pharmacal research 2020 Aug;43(8):821-862
Fucoidan A2 from the Brown Seaweed Ascophyllum nodosum Lowers Lipid by Improving Reverse Cholesterol Transport in C57BL/6J Mice Fed a High-Fat Diet.
Yang Z, Liu G, Wang Y, Yin J, Wang J, Xia B, Li T, Yang X, Hou P, Hu S, Song W, Guo S
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Journal of agricultural and food chemistry 2019 May 22;67(20):5782-5791
Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα.
Yang S, Wei L, Xia R, Liu L, Chen Y, Zhang W, Li Q, Feng K, Yu M, Zhang W, Qu J, Xu S, Mao J, Fan G, Ma C
Biochemical and biophysical research communications 2019 May 14;512(4):770-778
Biochemical and biophysical research communications 2019 May 14;512(4):770-778
Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Yang Y, Sun Q, Xu X, Yang X, Gao Y, Sun X, Zhao Y, Ding Z, Ge W, Cheng R, Zhang J
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Journal of agricultural and food chemistry 2019 Dec 4;67(48):13307-13317
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
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