Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 17355-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17355-1-AP, RRID:AB_2273677
- Product name
- ACTL7A antibody
- Antibody type
- Polyclonal
- Description
- ACTL7A antibody (Cat. #17355-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Novel bi-allelic variants in ACTL7A are associated with male infertility and total fertilization failure.
Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice.
Loss of SPACA1 function causes autosomal recessive globozoospermia by damaging the acrosome-acroplaxome complex.
Wang J, Zhang J, Sun X, Lin Y, Cai L, Cui Y, Liu J, Liu M, Yang X
Human reproduction (Oxford, England) 2021 Nov 18;36(12):3161-3169
Human reproduction (Oxford, England) 2021 Nov 18;36(12):3161-3169
Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice.
Dai J, Zhang T, Guo J, Zhou Q, Gu Y, Zhang J, Hu L, Zong Y, Song J, Zhang S, Dai C, Gong F, Lu G, Zheng W, Lin G
American journal of human genetics 2021 Mar 4;108(3):469-481
American journal of human genetics 2021 Mar 4;108(3):469-481
Loss of SPACA1 function causes autosomal recessive globozoospermia by damaging the acrosome-acroplaxome complex.
Chen P, Saiyin H, Shi R, Liu B, Han X, Gao Y, Ye X, Zhang X, Sun Y
Human reproduction (Oxford, England) 2021 Aug 18;36(9):2587-2596
Human reproduction (Oxford, England) 2021 Aug 18;36(9):2587-2596
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 17355-1-AP(ACTL7A antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ACTL7A antibody 17355-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line