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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA006135 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA006135, RRID:AB_1848602
- Product name
- Anti-FLNC
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FLNC, Gene description: filamin C, gamma, Alternative Gene Names: ABP-280, ABPL, FLN2, Validated applications: ICC, IHC, Uniprot ID: Q14315, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias
Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery
Autophagy is affected in patients with hypokalemic periodic paralysis: an involvement in vacuolar myopathy?
Spatiotemporal Proteomic Profiling of Human Cerebral Development
Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice
Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy
FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy
Ohiri J, DellefaveâCastillo L, Tomar G, Wilsbacher L, Choudhury L, Barefield D, Fullenkamp D, Gacita A, Monroe T, Pesce L, Blancard M, Vaught L, George A, Demonbreun A, Puckelwartz M, McNally E
Journal of the American Heart Association 2024;13(10)
Journal of the American Heart Association 2024;13(10)
Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery
Wang B, Nash T, Zhang X, Rao J, Abriola L, Kim Y, Zakharov S, Kim M, Luo L, Morsink M, Liu B, Lock R, Fleischer S, Tamargo M, Bohnen M, Welch C, Chung W, Marx S, Surovtseva Y, Vunjak-Novakovic G, Fine B
Cell Reports Medicine 2023;4(3):100976
Cell Reports Medicine 2023;4(3):100976
Autophagy is affected in patients with hypokalemic periodic paralysis: an involvement in vacuolar myopathy?
Krag T, Holm-Yildiz S, Witting N, Vissing J
Acta Neuropathologica Communications 2021;9(1)
Acta Neuropathologica Communications 2021;9(1)
Spatiotemporal Proteomic Profiling of Human Cerebral Development
Djuric U, Rodrigues D, Batruch I, Ellis J, Shannon P, Diamandis P
Molecular & Cellular Proteomics 2017;16(9):1548-1562
Molecular & Cellular Proteomics 2017;16(9):1548-1562
Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice
Papizan J, Garry G, Brezprozvannaya S, McAnally J, Bassel-Duby R, Liu N, Olson E
Journal of Clinical Investigation 2017;127(10):3730-3740
Journal of Clinical Investigation 2017;127(10):3730-3740
Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy
Tucker N, McLellan M, Hu D, Ye J, Parsons V, Mills R, Clauss S, Dolmatova E, Shea M, Milan D, Scott N, Lindsay M, Lubitz S, Domian I, Stone J, Lin H, Ellinor P
Circulation: Cardiovascular Genetics 2017;10(6)
Circulation: Cardiovascular Genetics 2017;10(6)
FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy
Begay R, Tharp C, Martin A, Graw S, Sinagra G, Miani D, Sweet M, Slavov D, Stafford N, Zeller M, Alnefaie R, Rowland T, Brun F, Jones K, Gowan K, Mestroni L, Garrity D, Taylor M
JACC: Basic to Translational Science 2016;1(5):344-359
JACC: Basic to Translational Science 2016;1(5):344-359
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human skeletal muscle and liver tissues using HPA006135 antibody. Corresponding FLNC RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
