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- References [17]
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- Product number
- 16897-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16897-1-AP, RRID:AB_2230815
- Product name
- GPT/ ALT1 antibody
- Antibody type
- Polyclonal
- Description
- GPT/ ALT1 antibody (Cat. #16897-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrative bioinformatics and machine learning identify iron metabolism genes MAP4, GPT, and HIRIP3 as diagnostic biomarkers and therapeutic targets in Alzheimer's disease.
Selective Alanine Transporter Utilization Is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer.
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis.
Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma.
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
Real-time monitoring of glucose metabolism and effects of metformin on HepG2 cells using (13)C in-cell NMR spectroscopy.
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.
Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury.
Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Exosome-transmitted microRNA-133b inhibited bladder cancer proliferation by upregulating dual-specificity protein phosphatase 1.
T Cell Activation Depends on Extracellular Alanine.
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft.
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
An X, Zeng X, Yi Z, Cao M, Wang Y, Yu W, Ren Z
Frontiers in cellular neuroscience 2025;19:1610682
Frontiers in cellular neuroscience 2025;19:1610682
Selective Alanine Transporter Utilization Is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer.
Nie H, Liao L, Zielinski RJ, Gomez JA, Basi AV, Seeley EH, Tan L, Bilecz AJ, Zhou W, Liu H, Wang C, Wu S, Qi Y, Miyamoto T, Severi F, Goldman AR, Gu S, Sood AK, Jazaeri AA, Drapkin R, Claiborne DT, Zhang N, Lorenzi PL, Burks JK, Lengyel E, Gottlieb E, Zhang R
Cancer research 2025 Sep 15;85(18):3471-3489
Cancer research 2025 Sep 15;85(18):3471-3489
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Yao H, Li L, Dai Q, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis.
Li F, Vigder N, Ziehr DR, Kamiya M, Nguyen HN, Steinhauser ML, Kim EY, Oldham WM
bioRxiv : the preprint server for biology 2025 Jul 24;
bioRxiv : the preprint server for biology 2025 Jul 24;
Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma.
Bischoff ME, Shamsaei B, Yang J, Secic D, Vemuri B, Reisz JA, D'Alessandro A, Bartolacci C, Adamczak R, Schmidt L, Wang J, Martines A, Venkat J, Tcheuyap VT, Biesiada J, Behrmann CA, Vest KE, Brugarolas J, Scaglioni PP, Plas DR, Patra KC, Gulati S, Landero Figueroa JA, Meller J, Cunningham JT, Czyzyk-Krzeska MF
Cancer discovery 2025 Feb 7;15(2):401-426
Cancer discovery 2025 Feb 7;15(2):401-426
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
Li D, Yao H, Ren Y, Shang J, Han X, Cao X, Song T, Zeng X
General and comparative endocrinology 2024 Mar 1;348:114448
General and comparative endocrinology 2024 Mar 1;348:114448
Real-time monitoring of glucose metabolism and effects of metformin on HepG2 cells using (13)C in-cell NMR spectroscopy.
Teng M, Li Z, Gu Y, Fan Y, Wang D, Liu M, Li Y, Wei G, Huang Y
Biochemical and biophysical research communications 2024 Jan 29;694:149383
Biochemical and biophysical research communications 2024 Jan 29;694:149383
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
Mi W, You J, Li L, Zhu L, Xia X, Yang L, Li F, Xu Y, Bi J, Liu P, Chen L, Li F
Life metabolism 2024 Aug;3(4):loae016
Life metabolism 2024 Aug;3(4):loae016
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.
Dai W, Shen J, Yan J, Bott AJ, Maimouni S, Daguplo HQ, Wang Y, Khayati K, Guo JY, Zhang L, Wang Y, Valvezan A, Ding WX, Chen X, Su X, Gao S, Zong WX
The Journal of clinical investigation 2022 Dec 15;132(24)
The Journal of clinical investigation 2022 Dec 15;132(24)
Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury.
Wang S, Sun Y, Bai Y, Zhou N, Chen N, Miller EJ, Zhang Y, Li W
Mediators of inflammation 2020;2020:8094347
Mediators of inflammation 2020;2020:8094347
Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnación-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC
Cancer discovery 2020 Jul;10(7):1018-1037
Cancer discovery 2020 Jul;10(7):1018-1037
Exosome-transmitted microRNA-133b inhibited bladder cancer proliferation by upregulating dual-specificity protein phosphatase 1.
Cai X, Qu L, Yang J, Xu J, Sun L, Wei X, Qu X, Bai T, Guo Z, Zhu Y
Cancer medicine 2020 Aug;9(16):6009-6019
Cancer medicine 2020 Aug;9(16):6009-6019
T Cell Activation Depends on Extracellular Alanine.
Ron-Harel N, Ghergurovich JM, Notarangelo G, LaFleur MW, Tsubosaka Y, Sharpe AH, Rabinowitz JD, Haigis MC
Cell reports 2019 Sep 17;28(12):3011-3021.e4
Cell reports 2019 Sep 17;28(12):3011-3021.e4
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, Calder EL, Carelli V, Denton TT, Beal MF, Gross SS, Manfredi G, D'Aurelio M
Cell metabolism 2018 May 1;27(5):1007-1025.e5
Cell metabolism 2018 May 1;27(5):1007-1025.e5
Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft.
Bharti SK, Mironchik Y, Wildes F, Penet MF, Goggins E, Krishnamachary B, Bhujwalla ZM
Oncotarget 2018 Mar 16;9(20):15326-15339
Oncotarget 2018 Mar 16;9(20):15326-15339
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Qin S, Zhou Y, Gray L, Kusebauch U, McEvoy L, Antoine DJ, Hampson L, Park KB, Campbell D, Caballero J, Glusman G, Yan X, Kim TK, Yuan Y, Wang K, Rowen L, Moritz RL, Omenn GS, Pirmohamed M, Hood L
Journal of proteome research 2016 Oct 7;15(10):3724-3740
Journal of proteome research 2016 Oct 7;15(10):3724-3740
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GPT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GPT. This antibody recognizes human, mouse antigen. The GPT antibody has been validated for the following applications: ELISA, WB analysis.
