Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11177-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11177-1-AP, RRID:AB_2156772
- Product name
- OGFR antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OGFR antibody (Cat. #11177-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Methionine enkephalin suppresses lung cancer metastasis by regulating the polarization of tumor-associated macrophages and the distribution of myeloid-derived suppressor cells in the tumor microenvironment and inhibiting epithelial-mesenchymal transition.
In vitro and in vivo killing effects of methionine enkephalin on osteosarcoma.
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Opioid Receptor Expression in Colorectal Cancer: A Nested Matched Case-Control Study.
Methionine enkephalin inhibited cervical carcinoma via apoptosis promotion and reduction of myeloid derived suppressor cell infiltrated in tumor.
Methionine enkephalin inhibits colorectal cancer by remodeling the immune status of the tumor microenvironment.
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
Regulatory role of methionine enkephalin in myeloid-derived suppressor cells and macrophages in human cutaneous squamous cell carcinoma.
Methionine enkephalin activates autophagy and stimulates tumour cell immunogenicity in human cutaneous squamous cell carcinoma.
Androgen represses opioid growth factor receptor (OGFR) in human prostate cancer LNCaP cells and OGFR expression in human prostate cancer tissue.
The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin.
Methionine enkephalin (MENK) inhibits human gastric cancer through regulating tumor associated macrophages (TAMs) and PI3K/AKT/mTOR signaling pathway inside cancer cells.
Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.
Zhang S, Geng J, Shan F, Shan Y, Griffin N, Wu B, Wang X
International immunopharmacology 2023 May;118:110064
International immunopharmacology 2023 May;118:110064
In vitro and in vivo killing effects of methionine enkephalin on osteosarcoma.
Huang H, Wang X, Zhang S, Bai X, Griffin N, Shan Y, Shan F
International immunopharmacology 2023 Dec;125(Pt B):111226
International immunopharmacology 2023 Dec;125(Pt B):111226
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Liu C, Cheng X, Xing J, Li J, Li Z, Jian D, Wang Y, Wang S, Li R, Zhang W, Shao D, Ma X, Chen X, Shen J, Shi C, Guo Z, Wang W, Fan T, Liu L, Tang H
International journal of biological sciences 2022;18(7):2882-2897
International journal of biological sciences 2022;18(7):2882-2897
Opioid Receptor Expression in Colorectal Cancer: A Nested Matched Case-Control Study.
Belltall A, Mazzinari G, Garrido-Cano I, Giner F, MarĂ AM, Eroles P, Argente-Navarro MP, Cata JP, Diaz-Cambronero O
Frontiers in oncology 2022;12:801714
Frontiers in oncology 2022;12:801714
Methionine enkephalin inhibited cervical carcinoma via apoptosis promotion and reduction of myeloid derived suppressor cell infiltrated in tumor.
Qu N, Wang R, Meng Y, Liu N, Zhai J, Shan F
International immunopharmacology 2022 Sep;110:108933
International immunopharmacology 2022 Sep;110:108933
Methionine enkephalin inhibits colorectal cancer by remodeling the immune status of the tumor microenvironment.
Wang X, Li S, Yan S, Shan Y, Wang X, Jingbo Z, Wang Y, Shan F, Griffin N, Sun X
International immunopharmacology 2022 Oct;111:109125
International immunopharmacology 2022 Oct;111:109125
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
Zhang S, Huang H, Handley M, Griffin N, Bai X, Shan F
International immunopharmacology 2021 Oct;99:107999
International immunopharmacology 2021 Oct;99:107999
Regulatory role of methionine enkephalin in myeloid-derived suppressor cells and macrophages in human cutaneous squamous cell carcinoma.
Bai X, Shan F, Qu N, Huang H, Handley M, Griffin N, Zhang S, Cao X
International immunopharmacology 2021 Oct;99:107996
International immunopharmacology 2021 Oct;99:107996
Methionine enkephalin activates autophagy and stimulates tumour cell immunogenicity in human cutaneous squamous cell carcinoma.
Bai X, Cao X, Qu N, Huang H, Handley M, Zhang S, Shan F
International immunopharmacology 2021 Jul;96:107733
International immunopharmacology 2021 Jul;96:107733
Androgen represses opioid growth factor receptor (OGFR) in human prostate cancer LNCaP cells and OGFR expression in human prostate cancer tissue.
Yamashita H, Shuman L, Warrick JI, Raman JD, Degraff DJ
American journal of clinical and experimental urology 2018;6(4):164-171
American journal of clinical and experimental urology 2018;6(4):164-171
The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin.
Wang X, Tian J, Jiao X, Geng J, Wang R, Liu N, Gao X, Griffin N, Gao Y, Shan F
Cancer management and research 2018;10:4773-4787
Cancer management and research 2018;10:4773-4787
Methionine enkephalin (MENK) inhibits human gastric cancer through regulating tumor associated macrophages (TAMs) and PI3K/AKT/mTOR signaling pathway inside cancer cells.
Wang X, Jiao X, Meng Y, Chen H, Griffin N, Gao X, Shan F
International immunopharmacology 2018 Dec;65:312-322
International immunopharmacology 2018 Dec;65:312-322
Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.
Suzuki M, Chiwaki F, Sawada Y, Ashikawa M, Aoyagi K, Fujita T, Yanagihara K, Komatsu M, Narita M, Suzuki T, Nagase H, Kushima R, Sakamoto H, Fukagawa T, Katai H, Nakagama H, Yoshida T, Uezono Y, Sasaki H
PloS one 2015;10(4):e0123407
PloS one 2015;10(4):e0123407
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 11177-1-AP(OGFR antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-OGFR (IP:11177-1-AP, 5ug; Detection:11177-1-AP 1:500) with COLO 320 cells lysate 1200ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OGFR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OGFR. This antibody recognizes human, mouse antigen. The OGFR antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.