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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 14168-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14168-1-AP, RRID:AB_2271861
- Product name
- Talin-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Talin-1 antibody (Cat. #14168-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration.
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration.
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Superhydrophilic and topography-regulatable surface grafting on PEEK to improve cellular affinity.
Cas phosphorylation regulates focal adhesion assembly.
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Talin1 regulates glucose metabolism and endometrial receptivity via GLUT-4 in patients with polycystic ovary syndrome and insulin resistance.
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2.
Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia.
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.
In Vivo and In Vitro Fibroblasts' Behavior and Capsular Formation in Correlation with Smooth and Textured Silicone Surfaces.
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Altered Glycosylation in the Aging Heart.
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes.
Comparison of Macrophage Activation Using γ-Globulin and Serum-derived Macrophage Activating Factor.
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.
Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.
Zhang JJ, Li X, Tian Y, Zou JK, Gan D, Deng DK, Jiao C, Yin Y, Tian BM, Wu RX, Chen FM, He XT
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration.
Kosinski J, Sechi A, Hain J, Villwock S, Ha SA, Hauschulz M, Rose M, Steib F, Ortiz-Brüchle N, Heij L, Maas SL, van der Vorst EPC, Knoesel T, Altendorf-Hofmann A, Simon R, Sauter G, Bednarsch J, Jonigk D, Dahl E
Molecular oncology 2024 Jun;18(6):1486-1509
Molecular oncology 2024 Jun;18(6):1486-1509
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Wang X, Xu H, Ning F, Duan S, Hu Y, Ding X, Xu FJ
Macromolecular rapid communications 2024 Jun 24;:e2400339
Macromolecular rapid communications 2024 Jun 24;:e2400339
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Kersey AL, Cheng DY, Deo KA, Dubell CR, Wang TC, Jaiswal MK, Kim MH, Murali A, Hargett SE, Mallick S, Lele TP, Singh I, Gaharwar AK
Biomaterials 2024 Apr;306:122473
Biomaterials 2024 Apr;306:122473
Superhydrophilic and topography-regulatable surface grafting on PEEK to improve cellular affinity.
Zhang B, Leng J, Ouyang Z, Yang Z, Zhang Q, Li Q, Li D, Zhao H
Biomaterials advances 2023 Mar;146:213310
Biomaterials advances 2023 Mar;146:213310
Cas phosphorylation regulates focal adhesion assembly.
Kumar S, Stainer A, Dubrulle J, Simpkins C, Cooper JA
eLife 2023 Jul 25;12
eLife 2023 Jul 25;12
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Zhou G, Wang J, Ren L, Liu J, Li X, Zhang Y, Sang Y, Gao L, Li Y, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Talin1 regulates glucose metabolism and endometrial receptivity via GLUT-4 in patients with polycystic ovary syndrome and insulin resistance.
Li J, Chen S, Qin R, Liu X, Fan L, Wei M, Wei J, Lin J, Zheng F
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2231085
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2023 Dec;39(1):2231085
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2.
Hong WF, Zhu DX, Chen YJ, Shen XZ, Cui YH, Du SS, Liu TS, Liang L
Cancer letters 2023 Dec 1;578:216460
Cancer letters 2023 Dec 1;578:216460
Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia.
Cui D, Cui X, Xu X, Zhang W, Yu Y, Gao Y, Mei C, Zheng W
BMC cancer 2022 Sep 29;22(1):1027
BMC cancer 2022 Sep 29;22(1):1027
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.
Zhang Y, Sun L, Li H, Ai L, Ma Q, Qiao X, Yang J, Zhang H, Ou X, Wang Y, Chen G, Xue J, Zhu X, Zhao Y, Yang Y, Liu C
eLife 2022 Mar 14;11
eLife 2022 Mar 14;11
In Vivo and In Vitro Fibroblasts' Behavior and Capsular Formation in Correlation with Smooth and Textured Silicone Surfaces.
Huang SQ, Chen Y, Zhu Q, Zhang YM, Lei ZY, Zhou X, Fan DL
Aesthetic plastic surgery 2022 Jun;46(3):1164-1177
Aesthetic plastic surgery 2022 Jun;46(3):1164-1177
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Yao Q, Wang H, Chen H, Li Z, Jiang Y, Li Z, Wang J, Xing Y, Liu F, Yu D, Yin S
Molecular neurobiology 2022 Jan;59(1):386-404
Molecular neurobiology 2022 Jan;59(1):386-404
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Zhang B, Fan M, Fan J, Luo Y, Wang J, Wang Y, Liu B, Sun Y, Zhao Q, Hiscox JA, Nan Y, Zhou EM
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Altered Glycosylation in the Aging Heart.
Franzka P, Krüger L, Schurig MK, Olecka M, Hoffmann S, Blanchard V, Hübner CA
Frontiers in molecular biosciences 2021;8:673044
Frontiers in molecular biosciences 2021;8:673044
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
Liu L, Zhang Q, Xiao S, Sun Z, Ding S, Chen Y, Wang L, Yin X, Liao F, Jiang LH, Xue M, You Y
Frontiers in pharmacology 2021;12:606245
Frontiers in pharmacology 2021;12:606245
Expression of Talin-1 in endometriosis and its possible role in pathogenesis.
Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Wang Q, Tian X, Zhou W, Wang Y, Zhao H, Li J, Zhou X, Zhang H, Zhao T, Li P
Journal of diabetes research 2020;2020:3634974
Journal of diabetes research 2020;2020:3634974
Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes.
Huang X, Shi X, Hansen ME, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA
ACS nano 2020 Oct 27;14(10):13192-13202
ACS nano 2020 Oct 27;14(10):13192-13202
Comparison of Macrophage Activation Using γ-Globulin and Serum-derived Macrophage Activating Factor.
Akamatsu M, Mashiba R, Kawakatsu K, Ishikawa M, Nishikata T
Anticancer research 2020 Aug;40(8):4707-4710
Anticancer research 2020 Aug;40(8):4707-4710
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Nakamura H, Shimizu T, Takatani A, Suematsu T, Nakamura T, Kawakami A
Virus research 2019 Aug;269:197643
Virus research 2019 Aug;269:197643
Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.
Li X, Zhou X, Chen Y, Yu S, Chen X, Xia X, Shi X, Zhang Y, Fan D
Journal of materials science. Materials in medicine 2017 Sep 15;28(10):167
Journal of materials science. Materials in medicine 2017 Sep 15;28(10):167
Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.
Chen P, Lei L, Wang J, Zou X, Zhang D, Deng L, Wu D
Cancer science 2017 Jun;108(6):1157-1168
Cancer science 2017 Jun;108(6):1157-1168
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14168-1-AP(TLN1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TLN1 antibody 14168-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14168-1-AP(TLN1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14168-1-AP(TLN1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Talin-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Talin-1. This antibody recognizes human,mouse,rat antigen. The Talin-1 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
