27096-1-AP

antibody from Proteintech Group

Targeting: ITGAV CD51, MSK8, VNRA, VTNR

Provider product page for 27096-1-AP

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [33]
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Product number: 27096-1-AP - Provider product page
Provider: Proteintech Group
Product name: Integrin Alpha V antibody
Antibody type: Polyclonal
Description: Integrin Alpha V antibody (Cat. #27096-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ITGAV protein structure - 27096-1-AP shown in red.

Submitted references Role of Periostin in the Development of Nasal Hyperresponsiveness in Mice with Allergic Rhinitis.

Adachi Y, Ando Y, Nagaosa K, Maeno M, Yamashita M, Takenoya F, Shioda S, Hanazaki M, Sakai H, Chiba Y
International journal of molecular sciences 2026 Jan 23;27(3)

Dual Physiological Barriers Bypassed by a Silk-Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease.

Hu D, Li T, He J, Jiang Y, Wang Y, Sun J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 20;:e75342

3D pancreatic ductal adenocarcinoma desmoplastic model: Glycolysis facilitating stemness via ITGAV-PI3K-AKT-YAP1.

Guan X, Wu D, Zhu H, Zhu B, Wang Z, Xing H, Zhang X, Yan J, Guo Y, Lu Y
Biomaterials advances 2025 May;170:214215

Epithelial-Mesenchymal Plasticity in the D-Meso-Sonobe Mesothelioma Cell Line: A Putative Model of Epithelial-Mesenchymal Transition in Mesothelioma.

Okubo H, Hanamatsu Y, Saigo C, Hiroshi S, Takeuchi T
Thoracic cancer 2025 May;16(10):e70091

Controlled reversible methionine-selective sulfimidation of peptides.

He Z, Zhao X, Gao WY, Bao G, Li Y, Zuo Q, Song X, Mou LY, Sun W, Wang R
Science advances 2025 May 23;11(21):eadv8712

Identifying novel drug targets for calcific aortic valve disease through Mendelian randomization.

Xu D, Lu J, Yang Y, Hu W, Chen J, Xue J, Yang S, Cao N, Hu H, Qian N, Zhou D, Dai H, Wang J, Liu X
Atherosclerosis 2025 Mar;402:119110

KBU2046 exerts inhibition on chemokine gradient-mediated motility of esophageal squamous cell carcinoma through reducing integrin expression.

Li K, Chen J, Li W, Zhang Z, Xue Y, Zheng Y, Zhang Y, Zhang C, Bergan R, Zhao L
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167800

Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.

Teng X, Wang Y, Huang H, Ding Y, Wang J, Liu M, Song K, Shao L, Yu Y, Yang Z, Shen Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501112

C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade.

Su Y, Ao X, Long Y, Zhang Z, Zhang M, Zhang Z, Wei M, Shan S, Lu S, Yu Y, Xu B
Cellular signalling 2025 Jan;125:111513

Single-cell profiling transcriptomic reveals cellular heterogeneity and cellular crosstalk in breast cancer lymphatic node, bone, and brain metastases.

Zhu L, Liu M, Shang Y, Cheng J, Zhao H, Zhang J, Shen D
Scientific reports 2025 Jan 17;15(1):2217

Integrated multi-omics analysis revealed the molecular networks and potential targets of cellular senescence in Alzheimer's disease.

Xu Y, Liu S, Zhou Z, Qin H, Zhang Y, Zhang G, Ma H, Han X, Liu H, Liu Z
Human molecular genetics 2025 Feb 17;34(5):381-391

Saffold virus exploits integrin αvβ8 and sulfated glycosaminoglycans as cooperative attachment receptors for infection.

Okuwa T, Himeda T, Kobayashi K, Nomura N, Utani K, Koike S, Nakamura A, Higuchi M
Nature communications 2025 Dec 15;17(1):534

Excessive collagen type VII mediates pleural fibrosis via increasing extracellular matrix stiffness.

Li Q, He XL, Chen SJ, Niu Q, Cao TZ, Cui XL, Jia ZH, Zhang HD, Feng X, Jiang YH, Liang LM, Cheng PP, Hu SH, Xiong L, Wang M, Ye H, Ma WL
The Journal of clinical investigation 2025 Dec 15;135(24)

Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organization.

Cohen D, Lázaro-Diéguez F, Müsch A
Journal of cell science 2025 Dec 1;138(23)

A Study on Regulating OSCC Cell Function by Blocking Integrin αvβ3 With Cilengitide.

Zeng L, Nie H, Xiong H, Yang Z, Hu X, Su T
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Aug;54(7):597-606

Galectin-3-integrin α5β1 phase separation disrupted by advanced glycation end-products impairs diabetic wound healing in rodents.

Zhang Z, Zhao Z, Huang X, Zhou L, Jiang X, Wu H, Liu C, Huang K, Wen J, Liu Y, Miller MC, Zhao Z, He Z, Wang Y, Liu S, Huang L, Yuan L, Zeng R, Cen Z, Chen A, Chen Y, Zeng G, Liu W, Hong X, Ren M, Yan L, Zhang Y, Guan D, Tian X, Cai W, Tai G, Mayo KH, Zhou Y, Li Z, Chen S
Nature communications 2025 Aug 7;16(1):7287

Blocking the ADAM9/ITGAV Pathway Ameliorates Sepsis-Induced Acute Lung Injury by Promoting Macrophage Efferocytosis.

Li LZ, Gu WJ, Yuan XK, Fan WM, Zhang LM, Qu ZK, Zhao FZ, Yin HY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70845

An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disc degeneration.

Liu Y, Chao T, Li Y, Peng P, Ge G, Geng D, Dong L, Wang C
Nature communications 2025 Apr 16;16(1):3629

Unveiling the therapeutic potential: KBU2046 halts triple-negative breast cancer cell migration by constricting TGF-β1 activation in vitro.

Chen J, Dai S, Zhang G, Wei S, Zhao X, Zheng Y, Wang Y, Wang X, Liu Y, Zhao L
Oncology research 2024;32(11):1791-1802

Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study.

Packialakshmi B, Limerick E, Ackerman HC, Lin X, Nekhai S, Oliver JD 3rd, Stewart IJ, Knepper MA, Fitzhugh C, Zhou X
Frontiers in physiology 2024;15:1300667

Hypoxia-induced TGFBI maintains glioma stem cells by stabilizing EphA2.

Chen Z, Wang J, Peng P, Liu G, Dong M, Zhang X, Zhang Y, Yang X, Wan L, Xiang W, Zhang S, Zhang B, Wu Q, Yu X, Wan F
Theranostics 2024;14(15):5778-5792

Silk films with distinct surface topography modulate plasma membrane curvature to polarize macrophages.

Hu D, Li T, Bian H, Liu H, Wang P, Wang Y, Sun J
Materials today. Bio 2024 Oct;28:101193

Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway.

Dulloo I, Tellier M, Levet C, Chikh A, Zhang B, Blaydon DC, Webb CM, Kelsell DP, Freeman M
Molecular cell 2024 Jan 18;84(2):277-292.e9

DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.

Liu C, Xu J, Fan J, Liu C, Xie W, Kong H
Experimental cell research 2024 Feb 1;435(1):113909

Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.

Williams N, Silva F, Schmolke M
Antiviral research 2024 Aug;228:105951

Cleavage of periostin by MMP9 protects mice from kidney cystic disease.

Djaziri N, Burel C, Abbad L, Bakey Z, Piedagnel R, Lelongt B
PloS one 2023;18(12):e0294922

Dynamic Tensile Stress Promotes Regeneration of Achilles Tendon in a Panda Rope Bridge Technique Mice Model.

Li Z, Sun X, Shen C, Deng Z, Tang K, Xie Y, Chen L, Nie M
Annals of biomedical engineering 2023 Dec;51(12):2735-2748

Fibronectin type III domain-containing 5 improves aging-related cardiac dysfunction in mice.

Hu C, Zhang X, Hu M, Teng T, Yuan YP, Song P, Kong CY, Xu SC, Ma ZG, Tang QZ
Aging cell 2022 Mar;21(3):e13556

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.

Lin F, Li X, Wang X, Sun H, Wang Z, Wang X
Journal of experimental & clinical cancer research : CR 2022 Apr 7;41(1):129

Macrophages Cytokine Spp1 Increases Growth of Prostate Intraepithelial Neoplasia to Promote Prostate Tumor Progression.

Messex JK, Byrd CJ, Thomas MU, Liou GY
International journal of molecular sciences 2022 Apr 12;23(8)

The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.

Presle A, Frémont S, Salles A, Commere PH, Sassoon N, Berlioz-Torrent C, Gupta-Rossi N, Echard A
Current biology : CB 2021 May 24;31(10):2203-2213.e5

Bioinformatics combined with quantitative proteomics analyses and identification of potential biomarkers in cholangiocarcinoma.

Da Z, Gao L, Su G, Yao J, Fu W, Zhang J, Zhang X, Pei Z, Yue P, Bai B, Lin Y, Meng W, Li X
Cancer cell international 2020;20:130

Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients.

Plana E, Gálvez L, Medina P, Navarro S, Fornés-Ferrer V, Panadero J, Miralles M
International journal of molecular sciences 2020 Jun 28;21(13)

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