Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- MAB2528 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Integrin alpha V beta 5 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Integrin alpha V beta 5. Recognizes the human Integrin alpha V beta 5 heterodimer and does not recognize the alpha V subunit in association with any other beta subunits.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- P5H9
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer.
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target.
cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.
Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice.
Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells.
Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells.
Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells.
Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly.
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells.
Huang H, Dong Y, Zhang Y, Ru D, Wu Z, Zhang J, Shen M, Duan Y, Sun Y
Theranostics 2019;9(4):1047-1065
Theranostics 2019;9(4):1047-1065
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target.
Wei J, Marisetty A, Schrand B, Gabrusiewicz K, Hashimoto Y, Ott M, Grami Z, Kong LY, Ling X, Caruso H, Zhou S, Wang YA, Fuller GN, Huse J, Gilboa E, Kang N, Huang X, Verhaak R, Li S, Heimberger AB
The Journal of clinical investigation 2019 Jan 2;129(1):137-149
The Journal of clinical investigation 2019 Jan 2;129(1):137-149
cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.
Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, Iwata C, Nagano O, Saya H, Nishiyama N, Kataoka K, Yamasoba T
Journal of controlled release : official journal of the Controlled Release Society 2017 Sep 10;261:275-286
Journal of controlled release : official journal of the Controlled Release Society 2017 Sep 10;261:275-286
Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice.
Shen YH, Yang F, Wang H, Cai ZJ, Xu YP, Zhao A, Su Y, Zhang G, Zhu SX
PloS one 2016;11(1):e0147173
PloS one 2016;11(1):e0147173
Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells.
Burgett ME, Lathia JD, Roth P, Nowacki AS, Galileo DS, Pugacheva E, Huang P, Vasanji A, Li M, Byzova T, Mikkelsen T, Bao S, Rich JN, Weller M, Gladson CL
Oncotarget 2016 Jul 12;7(28):43852-43867
Oncotarget 2016 Jul 12;7(28):43852-43867
Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells.
Mathieu M, Iampietro M, Chuchana P, Guérit D, Djouad F, Noël D, Jorgensen C
The Journal of biological chemistry 2014 Mar 21;289(12):8402-12
The Journal of biological chemistry 2014 Mar 21;289(12):8402-12
Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells.
Dixon KO, O'Flynn J, van der Kooij SW, van Kooten C
Journal of leukocyte biology 2014 Aug;96(2):313-24
Journal of leukocyte biology 2014 Aug;96(2):313-24
Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly.
Wang L, Pedroja BS, Meyers EE, Garcia AL, Twining SS, Bernstein AM
PloS one 2012;7(3):e33915
PloS one 2012;7(3):e33915
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells.
Cabezón R, Sintes J, Llinàs L, Benitez-Ribas D
Immunology letters 2011 Jan 30;134(2):167-73
Immunology letters 2011 Jan 30;134(2):167-73
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Integrin alpha V beta 5 in HT1080 Human Cell Line. Integrin alpha V beta 5 was detected in immersion fixed HT1080 human fibrosarcoma cell line using Human Integrin alpha V beta 5 Monoclonal Antibody (Catalog # MAB2528) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.