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Learn55117-1-AP
antibody from Proteintech Group
Targeting: EGR1
AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 55117-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- EGR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EGR1 antibody (Cat. #55117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Termination of convulsion seizures by destabilizing and perturbing seizure memory engrams.
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Zinc finger transcription factor Egf1 promotes non-alcoholic fatty liver disease.
Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy.
Lentinan induces apoptosis of mouse hepatocellular carcinoma cells through the EGR1/PTEN/AKT signaling axis.
DDIT3 aggravates pulpitis by modulating M1 polarization through EGR1 in macrophages.
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice.
The Role of Early Growth Response Family Members 1-4 in Prognostic Value of Breast Cancer.
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation.
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
MnO(2)-DNAzyme-photosensitizer nanocomposite with AIE characteristic for cell imaging and photodynamic-gene therapy.
Early growth response protein-1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease.
Podocyte histone deacetylase activity regulates murine and human glomerular diseases.
Hepatic miR-181b-5p Contributes to Glycogen Synthesis Through Targeting EGR1.
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Lai S, Zhang L, Tu X, Ma X, Song Y, Cao K, Li M, Meng J, Shi Y, Wu Q, Yang C, Lan Z, Lau CG, Shi J, Ma W, Li S, Xue YX, Huang Z
Science advances 2024 Mar 22;10(12):eadk9484
Science advances 2024 Mar 22;10(12):eadk9484
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A
Oncogene 2023 May;42(20):1607-1619
Oncogene 2023 May;42(20):1607-1619
Zinc finger transcription factor Egf1 promotes non-alcoholic fatty liver disease.
Guo Y, Miao X, Sun X, Li L, Zhou A, Zhu X, Xu Y, Wang Q, Li Z, Fan Z
JHEP reports : innovation in hepatology 2023 Jun;5(6):100724
JHEP reports : innovation in hepatology 2023 Jun;5(6):100724
Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy.
Fu W, Yang R, Li J
BMC biology 2023 Jun 6;21(1):132
BMC biology 2023 Jun 6;21(1):132
Lentinan induces apoptosis of mouse hepatocellular carcinoma cells through the EGR1/PTEN/AKT signaling axis.
You J, Wu Q, Li Y, Li X, Lin Z, Huang J, Xue Y, Gulimiran A, Pan Y
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
DDIT3 aggravates pulpitis by modulating M1 polarization through EGR1 in macrophages.
Wang Y, He Y, Dong W, Jia M, Yang C, Wang J
International immunopharmacology 2023 Jul;120:110328
International immunopharmacology 2023 Jul;120:110328
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
Sun B, Zhang Y, Zhang M, Liu R, Yang W
International journal of molecular medicine 2023 Feb;51(2)
International journal of molecular medicine 2023 Feb;51(2)
IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice.
Ma ZG, Yuan YP, Fan D, Zhang X, Teng T, Song P, Kong CY, Hu C, Wei WY, Tang QZ
Nature communications 2023 Aug 16;14(1):4967
Nature communications 2023 Aug 16;14(1):4967
The Role of Early Growth Response Family Members 1-4 in Prognostic Value of Breast Cancer.
Hao L, Huang F, Yu X, Xu B, Liu Y, Zhang Y, Zhu Y
Frontiers in genetics 2021;12:680132
Frontiers in genetics 2021;12:680132
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Sheng S, Zou M, Yang Y, Guan M, Ren S, Wang X, Wang L, Xue Y
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation.
Wang Y, Yao F, Wang L, Li Z, Ren Z, Li D, Zhang M, Han L, Wang SQ, Zhou B, Wang L
Nature communications 2020 May 22;11(1):2585
Nature communications 2020 May 22;11(1):2585
MicroRNA-217 ameliorates inflammatory damage of endothelial cells induced by oxidized LDL by targeting EGR1.
Yang X, Li D, Qi YZ, Chen W, Yang CH, Jiang YH
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
Molecular and cellular biochemistry 2020 Dec;475(1-2):41-51
MnO(2)-DNAzyme-photosensitizer nanocomposite with AIE characteristic for cell imaging and photodynamic-gene therapy.
Wang X, Dai J, Wang X, Hu Q, Huang K, Zhao Z, Lou X, Xia F
Talanta 2019 Sep 1;202:591-599
Talanta 2019 Sep 1;202:591-599
Early growth response protein-1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease.
Yang YL, Hu F, Xue M, Jia YJ, Zheng ZJ, Li Y, Xue YM
American journal of physiology. Cell physiology 2019 Mar 1;316(3):C340-C352
American journal of physiology. Cell physiology 2019 Mar 1;316(3):C340-C352
Podocyte histone deacetylase activity regulates murine and human glomerular diseases.
Inoue K, Gan G, Ciarleglio M, Zhang Y, Tian X, Pedigo CE, Cavanaugh C, Tate J, Wang Y, Cross E, Groener M, Chai N, Wang Z, Justice A, Zhang Z, Parikh CR, Wilson FP, Ishibe S
The Journal of clinical investigation 2019 Mar 1;129(3):1295-1313
The Journal of clinical investigation 2019 Mar 1;129(3):1295-1313
Hepatic miR-181b-5p Contributes to Glycogen Synthesis Through Targeting EGR1.
Wang S, Liang C, Ai H, Yang M, Yi J, Liu L, Song Z, Bao Y, Li Y, Sun L, Zhao H
Digestive diseases and sciences 2019 Jun;64(6):1548-1559
Digestive diseases and sciences 2019 Jun;64(6):1548-1559
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Wang Q, Wang HX, Shen JY, Zhang R, Hong JW, Li Z, Chen G, Li MX, Ding Z, Li J, Zhang JP, Zhang MR, Xu LC
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2017 Apr 18;
Molecular neurobiology 2017 Apr 18;
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 55117-1-AP( EGR1 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EGR1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human EGR1. This antibody recognizes human, mouse antigen. The EGR1 antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
