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- Antibody Data
- Antigen structure
- References [17]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 60258-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CD11c/Integrin Alpha X antibody
- Antibody type
- Monoclonal
- Description
- CD11c/Integrin Alpha X antibody (Cat. #60258-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2F1C10
- Vial size
- 20ul, 150ul
Submitted references Successful treatment with guselkumab of anti-p200 pemphigoid associated with plaque psoriasis.
Invasion characteristics and clinical significance of tumor-associated macrophages in gastrointestinal Krukenberg tumors.
CCL19(+) dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer.
Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice.
Tissue-resident FOLR2(+) macrophages associate with CD8(+) T cell infiltration in human breast cancer.
Morphological analysis of cell distribution and network structure via gap junctions in swine corneal stroma.
Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling‒Mediated Sensory Neuron‒Dendritic Cell Communication.
In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization.
Case Report: Dendritic Cells and Macrophages Capture Sperm in Chronically Inflamed Human Epididymis.
AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
Growth differentiation factor-15 promotes immune escape of ovarian cancer via targeting CD44 in dendritic cells.
Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden.
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation.
Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.
The Extracellular Domain of the β(2) Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity.
Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes.
Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells.
Kitayama S, Makino T, Kataoka K, Mori S, Takemoto K, Furukawa F, Torai R, Hayashi M, Mizawa M, Ishii N, Hashimoto T, Shimizu T
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2024 May;22(5):713-715
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2024 May;22(5):713-715
Invasion characteristics and clinical significance of tumor-associated macrophages in gastrointestinal Krukenberg tumors.
Huang Z, Li B, Qin H, Mo X
Frontiers in oncology 2023;13:1006183
Frontiers in oncology 2023;13:1006183
CCL19(+) dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer.
Wu SY, Zhang SW, Ma D, Xiao Y, Liu Y, Chen L, Song XQ, Ma XY, Xu Y, Chai WJ, Jin X, Shao ZM, Jiang YZ
Med (New York, N.Y.) 2023 Jun 9;4(6):373-393.e8
Med (New York, N.Y.) 2023 Jun 9;4(6):373-393.e8
Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice.
Asano M, Kajita K, Fuwa M, Kajita T, Mori I, Akahoshi N, Ishii I, Morita H
Endocrinology 2023 Jan 9;164(3)
Endocrinology 2023 Jan 9;164(3)
Tissue-resident FOLR2(+) macrophages associate with CD8(+) T cell infiltration in human breast cancer.
Nalio Ramos R, Missolo-Koussou Y, Gerber-Ferder Y, Bromley CP, Bugatti M, Núñez NG, Tosello Boari J, Richer W, Menger L, Denizeau J, Sedlik C, Caudana P, Kotsias F, Niborski LL, Viel S, Bohec M, Lameiras S, Baulande S, Lesage L, Nicolas A, Meseure D, Vincent-Salomon A, Reyal F, Dutertre CA, Ginhoux F, Vimeux L, Donnadieu E, Buttard B, Galon J, Zelenay S, Vermi W, Guermonprez P, Piaggio E, Helft J
Cell 2022 Mar 31;185(7):1189-1207.e25
Cell 2022 Mar 31;185(7):1189-1207.e25
Morphological analysis of cell distribution and network structure via gap junctions in swine corneal stroma.
Hoshino N, Takehana K, Hosotani M, Kametani K, Iwasaki T, Hasegawa Y, Ueda H, Watanabe T
The Journal of veterinary medical science 2022 Dec 14;84(12):1621-1632
The Journal of veterinary medical science 2022 Dec 14;84(12):1621-1632
Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling‒Mediated Sensory Neuron‒Dendritic Cell Communication.
Yin Q, Sun L, Cai X, Lou F, Sun Y, Wang B, Jiang B, Bao L, Li X, Song N, Tang S, Bai J, Wang Z, Wu Y, Zhou H, Wang H, Yu B, Li Q, Wang H
The Journal of investigative dermatology 2022 Aug;142(8):2173-2183.e6
The Journal of investigative dermatology 2022 Aug;142(8):2173-2183.e6
In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization.
Moysi E, Del Rio Estrada PM, Torres-Ruiz F, Reyes-Terán G, Koup RA, Petrovas C
Frontiers in immunology 2021;12:683396
Frontiers in immunology 2021;12:683396
Case Report: Dendritic Cells and Macrophages Capture Sperm in Chronically Inflamed Human Epididymis.
Zheng W, Zhang S, Chen X, Jiang S, Li Z, Li M
Frontiers in immunology 2021;12:629680
Frontiers in immunology 2021;12:629680
AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
Fukuda K, Okamura K, Riding RL, Fan X, Afshari K, Haddadi NS, McCauley SM, Guney MH, Luban J, Funakoshi T, Yaguchi T, Kawakami Y, Khvorova A, Fitzgerald KA, Harris JE
The Journal of experimental medicine 2021 Sep 6;218(9)
The Journal of experimental medicine 2021 Sep 6;218(9)
Growth differentiation factor-15 promotes immune escape of ovarian cancer via targeting CD44 in dendritic cells.
Gao Y, Xu Y, Zhao S, Qian L, Song T, Zheng J, Zhang J, Chen B
Experimental cell research 2021 May 1;402(1):112522
Experimental cell research 2021 May 1;402(1):112522
Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden.
Muto S, Ozaki Y, Yamaguchi H, Mine H, Takagi H, Watanabe M, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H
Oncology letters 2021 Mar;21(3):203
Oncology letters 2021 Mar;21(3):203
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation.
Zhan X, Guo S, Li Y, Ran H, Huang H, Mi L, Wu J, Wang X, Xiao D, Chen L, Li D, Zhang S, Yan X, Yu Y, Li T, Han Q, He K, Cui J, Li T, Zhou T, Rich JN, Bao S, Zhang X, Li A, Man J
The Journal of experimental medicine 2020 May 4;217(5)
The Journal of experimental medicine 2020 May 4;217(5)
Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.
Mustafa T, Li Q, Kelly LE, Gibbon A, Ryan I, Roffey K, Simonds S, Cowley MA, Sleeman MW
PloS one 2019;14(4):e0214621
PloS one 2019;14(4):e0214621
The Extracellular Domain of the β(2) Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity.
Ristow LC, Tran V, Schwartz KJ, Pankratz L, Mehle A, Sauer JD, Welch RA
mBio 2019 Jul 9;10(4)
mBio 2019 Jul 9;10(4)
Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes.
Anquetil F, Mondanelli G, Gonzalez N, Rodriguez Calvo T, Zapardiel Gonzalo J, Krogvold L, Dahl-Jørgensen K, Van den Eynde B, Orabona C, Grohmann U, von Herrath MG
Diabetes 2018 Sep;67(9):1858-1866
Diabetes 2018 Sep;67(9):1858-1866
Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells.
Umazume T, Thomas WM, Campbell S, Aluri H, Thotakura S, Zoukhri D, Makarenkova HP
Investigative ophthalmology & visual science 2015 Dec;56(13):8392-402
Investigative ophthalmology & visual science 2015 Dec;56(13):8392-402
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human tonsillitis using 60258-1-Ig(ITGAX antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD11c/Integrin alpha X antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human CD11c/Integrin alpha X. This antibody recognizes human,mouse antigen. The CD11c/Integrin alpha X antibody has been validated for the following applications: ELISA, IHC analysis.
