Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8149 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PDLIM3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PDLIM3.
- Description
- ALP (actinin-associated LIM protein), also known as PDLIM3 (PDZ and LIM domain protein 3) is a 364 amino acid protein that contains one LIM zinc-binding domain and one PDZ domain and localizes to the cytoplasm, as well as to myofiber Z-lines. Existing as three alternatively spliced isoforms, two of which exhibit tissue-specific expression in skeletal muscle and heart, ALP interacts with Ï«-actinin-2 and, via this interaction, is thought to play a role in Actin filament organization, specifically regulating the association of Actin filaments arrays with muscle cells. The gene encoding ALP maps to a region on human chromosome 4 that is associated with facioscapulohumeral muscular dystrophy, suggesting that defects in the ALP gene may be involved in the pathogenesis of muscular dystrophy.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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