GTX20657

antibody from GeneTex

Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7

Western blot (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Blocking/Neutralizing (Data presented on provider website)

Antibody Data

Product number

GTX20657

Provider

GeneTex

Proper citation

GeneTex Cat#GTX20657, RRID:AB_371916

Product name

CD18 antibody [MEM-48]

Antibody type

Monoclonal

Reactivity

Human, Mouse

Host

Mouse

References

Submitted references

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.

Tran DQ, Glass DD, Uzel G, Darnell DA, Spalding C, Holland SM, Shevach EM
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2929-38

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Human leukocytes contain a large pool of free forms of CD18.

Drbal K, Angelisová P, Cerný J, Pavlistová D, Cebecauer M, Novák P, Horejsí
Biochemical and biophysical research communications 2000 Aug 28;275(2):295-9

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Western Blot analysis (non-reducing conditions) of whole cell lysate using anti-human CD18 (GTX20657). Lane 1:?KG-1a human acute myeloid leukemia cell line Lane 2:?HPB-ALL human peripheral blood T cell leukemia cell line

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemistry staining of human spleen (paraffin sections) using anti-CD18 (GTX20657).

Flow cytometry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Surface staining of human peripheral blood cells with anti-human CD18: PE (GTX79945). Cells in the granulocyte gate were used for analysis.