MAB7917

antibody from Abnova Corporation

Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB7917

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB7917, RRID:AB_10674349

Product name

Itgb2 monoclonal antibody, clone M18/2

Antibody type

Monoclonal

Antigen

Native purified Itgb2 from mouse cytotoxic T cell glycoproteins.

Reactivity

Mouse

Host

Rat

Isotype

IgG

Vial size

100 µg

Storage

Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Neutrophil-selective CD18 silencing using RNA interference in vivo.

Cullere X, Lauterbach M, Tsuboi N, Mayadas TN
Blood 2008 Apr 1;111(7):3591-8

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Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation.

Varga G, Balkow S, Wild MK, Stadtbaeumer A, Krummen M, Rothoeft T, Higuchi T, Beissert S, Wethmar K, Scharffetter-Kochanek K, Vestweber D, Grabbe S
Blood 2007 Jan 15;109(2):661-9

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CD18 deficiency protects against multiple low-dose streptozotocin-induced diabetes.

Barlow SC, Langston W, Matthews KM, Chidlow JH Jr, Kevil CG
The American journal of pathology 2004 Dec;165(6):1849-52

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Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization.

Sakurai E, Taguchi H, Anand A, Ambati BK, Gragoudas ES, Miller JW, Adamis AP, Ambati J
Investigative ophthalmology & visual science 2003 Jun;44(6):2743-9

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Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1.

Abraham C, Miller J
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 1;167(9):5193-201