10554-1-AP

antibody from Proteintech Group

Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7

Provider product page for 10554-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [29]
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Product number: 10554-1-AP - Provider product page
Provider: Proteintech Group
Product name: CD18 antibody
Antibody type: Polyclonal
Description: CD18 antibody (Cat. #10554-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ITGB2 protein structure - 10554-1-AP shown in red.

Submitted references Sevoflurane blocks KLF5-mediated transcriptional activation of ITGB2 to inhibit macrophage infiltration in hepatic ischemia/reperfusion injury.

Li Y, Gao W, Lei S, Wu X, Yuan T, Ma K, Chi K
The journal of gene medicine 2024 May;26(5):e3692

Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8(+) T cells in cerebral malaria.

Wang Y, Shen Y, Liang J, Wang S, Huang Y, Zhu Q, Zhang X, Yu K, Tong G, Yang C, Li Y, Wang J, Zhao Y
Journal of neuroinflammation 2024 May 7;21(1):119

CD8(+) T cell infiltration and proliferation in the brainstem during experimental cerebral malaria.

Wang J, Zhu Q, Shen Y, Liang J, Wang Y, Huang Y, Tong G, Wang X, Zhang N, Yu K, Li Y, Zhao Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14431

Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.

Liu Y, Luo H, Liu B, Zhou T, Zhang Z, Liu Z
Biomacromolecules 2024 Jul 8;25(7):4557-4568

Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.

Zhou M, Wu Y, Sun M, Qin Y, Zhao J, Qiu Z, Li C, Zhang Y, Xiong Y, Shen Y, Zou Z, Tu J, Shen W, Sun C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888

Regulating Blood Clot Fibrin Films to Manipulate Biomaterial-Mediated Foreign Body Responses.

Zou Y, Shan Z, Han Z, Yang J, Lin Y, Gong Z, Xie L, Xu J, Xie R, Chen Z, Chen Z
Research (Washington, D.C.) 2023;6:0225

Identification and validation of immune-associated NETosis subtypes and biomarkers in anti-neutrophil cytoplasmic antibody associated glomerulonephritis.

Tao M, He Y, Li L, Li Y, Liao W, Nie H, Gao P
Frontiers in immunology 2023;14:1177968

Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis.

Guo T, Chen L, Li F, Cao Y, Li D, Xiong Q, Ling Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115579

Regulation of CD18 stability by SIGIRR-modulated ubiquitination: new insights into the relationship between innate immune response and acute lung injury.

Tian F, Lei J, Ni Y, Zhong D, Xie N, Ma J, Wang H, Si S, Wu Y, Jiang T
The FEBS journal 2023 May;290(10):2721-2743

Long Noncoding RNA AC078850.1 Induces NLRP3 Inflammasome-Mediated Pyroptosis in Atherosclerosis by Upregulating ITGB2 Transcription via Transcription Factor HIF-1α.

Tian Y, Luo Q, Huang K, Sun T, Luo S
Biomedicines 2023 Jun 16;11(6)

Diethylaminoethyl-dextran and monocyte cell membrane coated 1,8-cineole delivery system for intracellular delivery and synergistic treatment of atherosclerosis.

Jiang F, Wu G, Yang H, Zhang Y, Shen X, Tao L
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127365

Endothelial CCRL2 induced by disturbed flow promotes atherosclerosis via chemerin-dependent β2 integrin activation in monocytes.

Tang C, Chen G, Wu F, Cao Y, Yang F, You T, Liu C, Li M, Hu S, Ren L, Lu Q, Deng W, Xu Y, Wang G, Jo H, Zhang Y, Wu Y, Zabel BA, Zhu L
Cardiovascular research 2023 Aug 7;119(9):1811-1824

Differential Gene Expression and Immune Cell Infiltration in Carotid Intraplaque Hemorrhage Identified Using Integrated Bioinformatics Analysis.

Lv X, Wang F, Sun M, Sun C, Fan X, Ma B, Yang Y, Ye Z, Liu P, Wen J
Frontiers in cardiovascular medicine 2022;9:818585

Identification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology.

Zhao D, Zhang X, Tang Y, Guo P, Ai R, Hou M, Wang Y, Yuan X, Cui L, Zhang Y, Zhao S, Li W, Wang Y, Sun X, Liu L, Dong S, Li L, Zhao W, Nan Y
Journal of hepatocellular carcinoma 2022;9:389-403

Bioinformatics Analysis Identified the Hub Genes, mRNA-miRNA-lncRNA Axis, and Signaling Pathways Involved in Rheumatoid Arthritis Pathogenesis.

Yang M, Zheng H, Su Y, Xu K, Yuan Q, Aihaiti Y, Cai Y, Xu P
International journal of general medicine 2022;15:3879-3893

Identification of key differential genes in intimal hyperplasia induced by left carotid artery ligation.

Zhang L, Gu J, Wang S, He F, Gong K
PeerJ 2022;10:e13436

Species-independent stimulation of osteogenic differentiation induced by osteoclasts.

Zhang Y, Polman M, Mohammad AF, Hermens I, Zhuang Z, Wang H, van den Beucken JJ
Biochemical and biophysical research communications 2022 May 28;606:149-155

Liu L, Zhao Q, Kong M, Mao L, Yang Y, Xu Y
Cardiovascular research 2022 Feb 21;118(3):844-858

Integrated Multiomics Analysis Identifies a Novel Biomarker Associated with Prognosis in Intracerebral Hemorrhage.

Shen Y, Yang W, Xiong X, Li X, Xiao Z, Yu J, Liu F, Gui S, Xie X, Lv F, Zhao L, Hu L, Manaenko A, Xie P, Li Q
Oxidative medicine and cellular longevity 2021;2021:2510847

Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.

Su VY, Chiou SH, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 May 24;22(11)

A Practical Procedure for the In Vitro Generation of Human Osteoclasts and Their Characterization.

Husch JFA, Stessuk T, den Breejen C, van den Boom M, Leeuwenburgh SCG, van den Beucken JJJP
Tissue engineering. Part C, Methods 2021 Jul;27(7):421-432

The cell surface hyaluronidase TMEM2 regulates cell adhesion and migration via degradation of hyaluronan at focal adhesion sites.

Irie F, Tobisawa Y, Murao A, Yamamoto H, Ohyama C, Yamaguchi Y
The Journal of biological chemistry 2021 Jan-Jun;296:100481

ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.

Zhang X, Dong Y, Zhao M, Ding L, Yang X, Jing Y, Song Y, Chen S, Hu Q, Ni Y
Theranostics 2020;10(26):12044-12059

Layilin augments integrin activation to promote antitumor immunity.

Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, Daud AI, Rosenblum MD
The Journal of experimental medicine 2020 Sep 7;217(9)

Leukocyte-Mediated Combined Targeted Chemo and Gene Therapy for Esophageal Cancer.

Jun Y, Tang Z, Luo C, Jiang B, Li X, Tao M, Gu H, Liu L, Zhang Z, Sun S, Han K, Yu X, Song X, Tao G, Chen X, Zhang L, Gao Y, Wang QL
ACS applied materials & interfaces 2020 Oct 21;12(42):47330-47341

Interaction between the integrin Mac-1 and signal regulatory protein α (SIRPα) mediates fusion in heterologous cells.

Podolnikova NP, Hlavackova M, Wu Y, Yakubenko VP, Faust J, Balabiyev A, Wang X, Ugarova TP
The Journal of biological chemistry 2019 May 10;294(19):7833-7849

Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin β2/FAK signaling pathway in ovarian cancer.

Li H, Hu S, Pang Y, Li M, Chen L, Liu F, Liu M, Wang Z, Cheng X
American journal of cancer research 2018;8(7):1288-1296

PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.

Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1817-1826

Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.

Xiong Y, Ye C, Yang N, Li M, Liu H
Journal of immunology (Baltimore, Md. : 1950) 2017 Dec 15;199(12):4142-4154

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