12-0189-41

antibody from Invitrogen Antibodies
Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7
Provider product page for 12-0189-41

Antibody data

Product number
12-0189-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD18 (LFA-1 beta) Monoclonal Antibody (6.7), PE, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The 6.7 monoclonal antibody reacts with human and non-human primate (rhesus or cynomologus) CD18, which is also known as beta2 integrin. CD18 is a 90-95 kDa type I transmembrane protein that heterodimerizes with the a chain of CD11a, CD11b and CD11c. The CD18/CD11a complex is also known as lymphocyte function-associated antigen-1 (LFA-1) and plays an important role in cellular adhesion and inflammatory reactions. CD18 is expressed broadly by human lymphocytes and monocytes. Peripheral blood granulocytes also express CD18, but at lower levels. The 6.7 monoclonal antibody has been reported to induce the proliferation of resting T cells cultured with monocytes. Applications Reported: This 6.7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 6.7 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Antibody clone number
6.7
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
ITGB2 protein structure - 12-0189-41 shown in red.