Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- ALX-805-062-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-805-062-C100, RRID:AB_2051022
- Product name
- CD18 (human) monoclonal antibody (MEM-48)
- Antibody type
- Monoclonal
- Antigen
- Purified from natural sources
- Description
- Protein A-affinity purified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- MEM-48
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20¡C.
Submitted references Regulation of CD18 expression on neutrophils in response to fluid shear stress.
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins.
Monoclonal Lym-1 antibody-targeted lysis of B lymphoma cells by neutrophils. Evidence for two mechanisms of FcgammaRII-dependent cytolysis.
Human leukocytes contain a large pool of free forms of CD18.
Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of FcgammaRII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins.
The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases.
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.
Fukuda S, Schmid-Schönbein GW
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 11;100(23):13152-7
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 11;100(23):13152-7
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
Drbal K, Angelisová P, Hilgert I, Cerný J, Novák P, Horejsí V
Blood 2001 Sep 1;98(5):1561-6
Blood 2001 Sep 1;98(5):1561-6
A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins.
Drbal K, Angelisová P, Cerný J, Hilgert I, Horejsí V
Immunobiology 2001 May;203(4):687-98
Immunobiology 2001 May;203(4):687-98
Monoclonal Lym-1 antibody-targeted lysis of B lymphoma cells by neutrophils. Evidence for two mechanisms of FcgammaRII-dependent cytolysis.
Ottonello L, Epstein AL, Mancini M, Amelotti M, Dapino P, Dallegri F
Journal of leukocyte biology 2000 Nov;68(5):662-8
Journal of leukocyte biology 2000 Nov;68(5):662-8
Human leukocytes contain a large pool of free forms of CD18.
Drbal K, Angelisová P, Cerný J, Pavlistová D, Cebecauer M, Novák P, Horejsí
Biochemical and biophysical research communications 2000 Aug 28;275(2):295-9
Biochemical and biophysical research communications 2000 Aug 28;275(2):295-9
Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of FcgammaRII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins.
Ottonello L, Epstein AL, Dapino P, Barbera P, Morone P, Dallegri F
Blood 1999 May 15;93(10):3505-11
Blood 1999 May 15;93(10):3505-11
The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases.
Cinek T, Horejsí V
Journal of immunology (Baltimore, Md. : 1950) 1992 Oct 1;149(7):2262-70
Journal of immunology (Baltimore, Md. : 1950) 1992 Oct 1;149(7):2262-70
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.
Bazil V, Stefanová I, Hilgert I, Kristofová H, Vanĕk S, Horejsí V
Folia biologica 1990;36(1):41-50
Folia biologica 1990;36(1):41-50
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