ABIN111902

antibody from antibodies-online

Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

ABIN111902

Provider

antibodies-online

Product name

anti-Integrin beta 2 (ITGB2) (Activation Site) antibody

Antibody type

Monoclonal

Description

Protein A Affinity Chromatography

Reactivity

Human

Host

Mouse

Epitope

Activation Site

Isotype

IgG

Antibody clone number

MEM-148

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The virological synapse facilitates herpes simplex virus entry into T cells.

Aubert M, Yoon M, Sloan DD, Spear PG, Jerome KR
Journal of virology 2009 Jun;83(12):6171-83

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Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects.

Dassanayake RP, Maheswaran SK, Srikumaran S
Infection and immunity 2007 Oct;75(10):5004-10

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CD18 in monogenic and polygenic inflammatory processes of the skin.

Peters T, Sindrilaru A, Wang H, Oreshkova T, Renkl AC, Kess D, Scharffetter-Kochanek K
The journal of investigative dermatology. Symposium proceedings 2006 Sep;11(1):7-15

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Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2.

Solovjov DA, Pluskota E, Plow EF
The Journal of biological chemistry 2005 Jan 14;280(2):1336-45

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CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis.

Kess D, Peters T, Zamek J, Wickenhauser C, Tawadros S, Loser K, Varga G, Grabbe S, Nischt R, Sunderkötter C, Müller W, Krieg T, Scharffetter-Kochanek K
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 1;171(11):5697-706

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A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.

Drbal K, Angelisová P, Hilgert I, Cerný J, Novák P, Horejsí V
Blood 2001 Sep 1;98(5):1561-6

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A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins.

Drbal K, Angelisová P, Cerný J, Hilgert I, Horejsí V
Immunobiology 2001 May;203(4):687-98

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Contribution of CD11a/CD18, CD11b/CD18, ICAM-1 (CD54) and -2 (CD102) to human monocyte migration through endothelium and connective tissue fibroblast barriers.

Shang XZ, Issekutz AC
European journal of immunology 1998 Jun;28(6):1970-9

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Mac-1 (CD11b/CD18) is the predominant beta 2 (CD18) integrin mediating human neutrophil migration through synovial and dermal fibroblast barriers.

Gao JX, Issekutz AC
Immunology 1996 Jul;88(3):463-70