RA0178

antibody from Oursmab

Targeting: CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0178

Provider

Oursmab

Product name

Quetmolimab (Biosimilar Reference Antibody) (CX3CL1)

Antibody type

Monoclonal

Description

Quetmolimab is a humanized IgG2 kappa monoclonal antibody that specifically targets chemokine ligand 1 (CX3CL1, also known as fractalkine). By binding to CX3CL1, it blocks the interaction between this soluble or membrane-bound chemokine and its receptor CX3CR1, thereby inhibiting the chemoattraction and adhesion of immune cells (such as monocytes and T cells) to sites of inflammation. This mechanism is being investigated for the treatment of inflammatory and autoimmune diseases, including rheumatoid arthritis and atherosclerosis.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Quetmolimab (Biosimilar Reference Antibody) (CX3CL1)-RA0178-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Quetmolimab (Biosimilar Reference Antibody) (CX3CL1)-RA0178 in a linear range of 15.63¨C125 ng/mL.