Ab176425
antibody from Aladdin Scientific
Targeting: STAB1
CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- ELISA [1]
- Flow cytometry [1]
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Validation data
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- Product number
- Ab176425 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Bexmarilimab (anti-STAB1)
- Antibody type
- Recombinant
- Description
- Bexmarilimab (anti-STAB1) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab (anti-STAB1) is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab (anti-STAB1) can be used in research of cancer. _Note: 50 in IC50 is a subscript_Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Bexmarilimab (anti-STAB1) (Ab176425) - ELISA STAB1 2 μg/mL can bind Bexmarilimab (anti-STAB1) (Ab176425) with the EC₅₀ of 7.27 ng/mL.
Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Bexmarilimab (anti-STAB1) (Ab176425) - Flow Cytometry Flow Cytometry analysis of MCF-7 cells labelling STAB1 (red) with Bexmarilimab (anti-STAB1) (Ab176425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.