Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- RP1081 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Livin/BIRC7 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for Livin/BIRC7 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: ELISA. Reactive species: Human. Livin/BIRC7 information: Molecular Weight: 32798 MW; Subcellular Localization: Nucleus . Cytoplasm . Golgi apparatus . Nuclear, and in a filamentous pattern throughout the cytoplasm. Full-length livin is detected exclusively in the cytoplasm, whereas the truncated form (tLivin) is found in the peri-nuclear region with marked localization to the Golgi apparatus; the accumulation of tLivin in the nucleus shows positive correlation with the increase in apoptosis; Tissue Specificity: Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Negative correlation of LIV-1 and E-cadherin expression in hepatocellular carcinoma cells.
Shen R, Xie F, Shen H, liu Q, Zheng T, Kou X, Wang D, Yang J
PloS one 2013;8(2):e56542
PloS one 2013;8(2):e56542
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