Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB0092 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB0092, RRID:AB_1018903
- Product name
- BIRC7 monoclonal antibody, clone 88C570
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein corresponding to full length human BIRC7.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma.
Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin.
Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells.
Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway.
Kleinberg L, Lie AK, Flørenes VA, Nesland JM, Davidson B
Human pathology 2007 Jul;38(7):986-94
Human pathology 2007 Jul;38(7):986-94
Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin.
Nachmias B, Lazar I, Elmalech M, Abed-El-Rahaman I, Asshab Y, Mandelboim O, Perlman R, Ben-Yehuda D
Apoptosis : an international journal on programmed cell death 2007 Jul;12(7):1129-42
Apoptosis : an international journal on programmed cell death 2007 Jul;12(7):1129-42
Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells.
Wang H, Tan SS, Wang XY, Liu DH, Yu CS, Bai ZL, He DL, Zhao J
Acta pharmacologica Sinica 2007 Dec;28(12):1968-74
Acta pharmacologica Sinica 2007 Dec;28(12):1968-74
Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.
Crnković-Mertens I, Semzow J, Hoppe-Seyler F, Butz K
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway.
Ma L, Huang Y, Song Z, Feng S, Tian X, Du W, Qiu X, Heese K, Wu M
Cell death and differentiation 2006 Dec;13(12):2079-88
Cell death and differentiation 2006 Dec;13(12):2079-88
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot detection of BIRC7 in A) BIRC7 transfected cell lysate and B) MOLT 4 cell lysate. A protein band of apprximate molecular weight of 31 KDa is detected using BIRC7 monoclonal antibody, clone 88C570 (Cat # MAB0092) at 2 ug/mL dilution.
- Validation comment
- Western Blot