Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- PAB14670 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB14670, RRID:AB_10550828
- Product name
- BIRC7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.
- Antigen sequence
PELPTPRREVQSESAQEPG
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.
Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.
Crnković-Mertens I, Semzow J, Hoppe-Seyler F, Butz K
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.
Wright CW, Duckett CS
The Journal of clinical investigation 2005 Oct;115(10):2673-8
The Journal of clinical investigation 2005 Oct;115(10):2673-8
Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.
Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, Peretz T, Mandelboim O, Ben-Yehuda D
Cancer research 2003 Oct 1;63(19):6340-9
Cancer research 2003 Oct 1;63(19):6340-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of full-length, recombinant human BIRC7 using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of BIRC7 in formalin-fixed, paraffin embedded human tonsil (secondary nodule) using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000. Hematoxylin-eosin counterstain.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of BIRC7 in Bouin's-fixed, paraffin-embedded E13.5 mouse embryo (13.5 days post coitum) Bouin's using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000. The mother was perfused prior to embryo harvesting. A, brain overview. B, brain. C, spinal cord. D, liver and abdominal wall. Hematoxylin-eosin counterstain.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)