Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN252506 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 88C570
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Inhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152.
tLivin displays flexibility by promoting alternative cell death mechanisms.
The clinical effect of the inhibitor of apopotosis protein livin in melanoma.
Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma.
DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells.
The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin.
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.
Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis.
Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma.
Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.
Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma.
Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin.
Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia.
Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells.
Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway.
Selectively frequent expression of CXCR5 enhances resistance to apoptosis in CD8(+)CD34(+) T cells from patients with T-cell-lineage acute lymphocytic leukemia.
CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation.
Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene.
Tchoghandjian A, Soubéran A, Tabouret E, Colin C, Denicolaï E, Jiguet-Jiglaire C, El-Battari A, Villard C, Baeza-Kallee N, Figarella-Branger D
Cell death & disease 2016 Aug 4;7(8):e2325
Cell death & disease 2016 Aug 4;7(8):e2325
tLivin displays flexibility by promoting alternative cell death mechanisms.
Shiloach T, Berens C, Danke C, Waiskopf O, Perlman R, Ben-Yehuda D
PloS one 2014;9(6):e101075
PloS one 2014;9(6):e101075
The clinical effect of the inhibitor of apopotosis protein livin in melanoma.
Lazar I, Perlman R, Lotem M, Peretz T, Ben-Yehuda D, Kadouri L
Oncology 2012;82(4):197-204
Oncology 2012;82(4):197-204
Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma.
Liu X, Wang A, Gao H, Yuan Z, Jiao Y
International journal of oncology 2012 Sep;41(3):1021-8
International journal of oncology 2012 Sep;41(3):1021-8
DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells.
Slagsvold JE, Pettersen CH, Størvold GL, Follestad T, Krokan HE, Schønberg SA
Nutrition and cancer 2010;62(5):611-21
Nutrition and cancer 2010;62(5):611-21
The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin.
Lazar I, Yaacov B, Shiloach T, Eliahoo E, Kadouri L, Lotem M, Perlman R, Zakay-Rones Z, Panet A, Ben-Yehuda D
Journal of virology 2010 Jan;84(1):639-46
Journal of virology 2010 Jan;84(1):639-46
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.
Fakler M, Loeder S, Vogler M, Schneider K, Jeremias I, Debatin KM, Fulda S
Blood 2009 Feb 19;113(8):1710-22
Blood 2009 Feb 19;113(8):1710-22
Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis.
Crnković-Mertens I, Wagener N, Semzow J, Gröne EF, Haferkamp A, Hohenfellner M, Butz K, Hoppe-Seyler F
Cellular and molecular life sciences : CMLS 2007 May;64(9):1137-44
Cellular and molecular life sciences : CMLS 2007 May;64(9):1137-44
Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma.
Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Edenfield HR, Glickman JN, Yeap BY, Sugarbaker DJ, Bueno R
The Journal of pathology 2007 Mar;211(4):447-54
The Journal of pathology 2007 Mar;211(4):447-54
Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.
Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Yeap BY, Sugarbaker DJ, Bueno R
The Journal of pathology 2007 Mar;211(4):439-46
The Journal of pathology 2007 Mar;211(4):439-46
Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma.
Kleinberg L, Lie AK, Flørenes VA, Nesland JM, Davidson B
Human pathology 2007 Jul;38(7):986-94
Human pathology 2007 Jul;38(7):986-94
Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin.
Nachmias B, Lazar I, Elmalech M, Abed-El-Rahaman I, Asshab Y, Mandelboim O, Perlman R, Ben-Yehuda D
Apoptosis : an international journal on programmed cell death 2007 Jul;12(7):1129-42
Apoptosis : an international journal on programmed cell death 2007 Jul;12(7):1129-42
Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia.
Choi J, Hwang YK, Sung KW, Lee SH, Yoo KH, Jung HL, Koo HH, Kim HJ, Kang HJ, Shin HY, Ahn HS
Blood 2007 Jan 15;109(2):471-7
Blood 2007 Jan 15;109(2):471-7
Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells.
Wang H, Tan SS, Wang XY, Liu DH, Yu CS, Bai ZL, He DL, Zhao J
Acta pharmacologica Sinica 2007 Dec;28(12):1968-74
Acta pharmacologica Sinica 2007 Dec;28(12):1968-74
Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.
Crnković-Mertens I, Semzow J, Hoppe-Seyler F, Butz K
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway.
Ma L, Huang Y, Song Z, Feng S, Tian X, Du W, Qiu X, Heese K, Wu M
Cell death and differentiation 2006 Dec;13(12):2079-88
Cell death and differentiation 2006 Dec;13(12):2079-88
Selectively frequent expression of CXCR5 enhances resistance to apoptosis in CD8(+)CD34(+) T cells from patients with T-cell-lineage acute lymphocytic leukemia.
Qiuping Z, Jie X, Youxin J, Qun W, Wei J, Chun L, Jin W, Yan L, Chunsong H, Mingzhen Y, Qingping G, Qun L, Kejian Z, Zhimin S, Junyan L, Jinquan T
Oncogene 2005 Jan 20;24(4):573-84
Oncogene 2005 Jan 20;24(4):573-84
CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation.
Qiuping Z, Jei X, Youxin J, Wei J, Chun L, Jin W, Qun W, Yan L, Chunsong H, Mingzhen Y, Qingping G, Kejian Z, Zhimin S, Qun L, Junyan L, Jinquan T
Cancer research 2004 Oct 15;64(20):7579-87
Cancer research 2004 Oct 15;64(20):7579-87
Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
Yang QH, Du C
The Journal of biological chemistry 2004 Apr 23;279(17):16963-70
The Journal of biological chemistry 2004 Apr 23;279(17):16963-70
Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.
Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, Peretz T, Mandelboim O, Ben-Yehuda D
Cancer research 2003 Oct 1;63(19):6340-9
Cancer research 2003 Oct 1;63(19):6340-9
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene.
Crnkovic-Mertens I, Hoppe-Seyler F, Butz K
Oncogene 2003 Nov 13;22(51):8330-6
Oncogene 2003 Nov 13;22(51):8330-6
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- Submitted by
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- Main image
- Experimental details
- WB