11467-1-AP

antibody from Proteintech Group

Targeting: SPDEF bA375E1.3, PDEF

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

11467-1-AP

Provider

Proteintech Group

Product name

SPDEF antibody

Antibody type

Polyclonal

Description

SPDEF antibody (Cat. #11467-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.

He H, Yuan J, Wang H, Chen L, Liu B, Cui Z, Xu Y, Zhang G, Yang H
Oncogene 2026 Apr;45(12):1071-1086

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Genkwanin reduces airway epithelial cell ferroptosis and alleviates asthma symptoms in mice.

Chen X, Liu J, An Z, Li M, Ji X, Huang J, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157306

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Cumulative experience meets modern science: Remarkable effects of TongXieYaoFang formula on facilitating intestinal mucosal healing and secretory function.

Du X, Liu L, Yang L, Zhang Y, Dong K, Li Y, Chen Y, Yang Q, Zhu X, Li Q
Journal of ethnopharmacology 2025 Feb 11;341:119370

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SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1.

Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Molecular medicine (Cambridge, Mass.) 2024 Dec 30;30(1):282

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Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway.

Hou Y, Zheng S, Zou F, Wang D, Da H, Zhou Y, Fan X, Liu J, Zhao H, He J, Li H, Sun X, Liu Y
Immunobiology 2023 Sep;228(5):152712

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Shaoyao decoction restores the mucus layer in mice with DSS-induced colitis by regulating Notch signaling pathway.

Fang YX, Liu YQ, Hu YM, Yang YY, Zhang DJ, Jiang CH, Wang JH, Zhang J
Journal of ethnopharmacology 2023 May 23;308:116258

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Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse.

Melis M, Tang XH, Mai K, Gudas LJ, Trasino SE
Pharmacology 2022;107(7-8):406-416

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Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.

Liang L, Liu L, Zhou W, Yang C, Mai G, Li H, Chen Y
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307

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EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.

Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420

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Compromised Ileal Mucus Barrier Due to Impaired Epithelial Homeostasis Caused by Notch1 Signaling in Cirrhotic Rats.

Zhang L, Tai Y, Tang S, Zhao C, Tong H, Gao J, Tang C
Digestive diseases and sciences 2021 Jan;66(1):131-142

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A modular master regulator landscape controls cancer transcriptional identity.

Paull EO, Aytes A, Jones SJ, Subramaniam PS, Giorgi FM, Douglass EF, Tagore S, Chu B, Vasciaveo A, Zheng S, Verhaak R, Abate-Shen C, Alvarez MJ, Califano A
Cell 2021 Jan 21;184(2):334-351.e20

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Resveratrol inhibits MUC5AC expression by regulating SPDEF in lung cancer cells.

Lin YH, Zhu LY, Yang YQ, Zhang ZH, Chen QG, Sun YP, Bi JJ, Luo XM, Ni ZH, Wang XB
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Aug;89:153601

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Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression.

Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M
Molecular carcinogenesis 2019 Jun;58(6):980-995