Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1673012 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human BCL2L3, different from the related mouse sequence by one amino acid.Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid repeated freezing and thawing.
Submitted references SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W
Nature 2011 Mar 3;471(7336):104-9
Nature 2011 Mar 3;471(7336):104-9
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
Schwickart M, Huang X, Lill JR, Liu J, Ferrando R, French DM, Maecker H, O'Rourke K, Bazan F, Eastham-Anderson J, Yue P, Dornan D, Huang DC, Dixit VM
Nature 2010 Jan 7;463(7277):103-7
Nature 2010 Jan 7;463(7277):103-7
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