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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- LS-C41333 - Provider product page
- Provider
- LSBio
- Proper citation
- LifeSpan Cat#LS-C41333, RRID:AB_2297720
- Product name
- Anti-MCL1 / MCL 1 Antibody LS-C41333
- Antibody type
- Polyclonal
- Description
- Immunoaffinity purified
- Reactivity
- Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 50µl
- Storage
- Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
Submitted references A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination.
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.
Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1.
The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation.
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.
Baumgartner CK, Yagita H, Malherbe LP
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 1;189(5):2309-17
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 1;189(5):2309-17
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.
Coloff JL, Mason EF, Altman BJ, Gerriets VA, Liu T, Nichols AN, Zhao Y, Wofford JA, Jacobs SR, Ilkayeva O, Garrison SP, Zambetti GP, Rathmell JC
The Journal of biological chemistry 2011 Feb 18;286(7):5921-33
The Journal of biological chemistry 2011 Feb 18;286(7):5921-33
Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1.
Hu L, Chen L, Li L, Sun H, Yang G, Chang Y, Tu Q, Wu M, Wang H
Journal of virology 2011 Apr;85(7):3214-28
Journal of virology 2011 Apr;85(7):3214-28
The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation.
Peperzak V, Veraar EA, Keller AM, Xiao Y, Borst J
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6670-8
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6670-8
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.
Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC
Molecular and cellular biology 2007 Jun;27(12):4328-39
Molecular and cellular biology 2007 Jun;27(12):4328-39
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Supportive validation
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- LSBio (provider)
- Main image
- Experimental details
- A20 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-Mcl-1 polyclonal antibody. Proteins were visualized using donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection
