ABIN121513

antibody from antibodies-online

Targeting: MCL1 BCL2L3, Mcl-1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN121513

Provider

antibodies-online

Product name

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 121-139) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to amino acids 121-139 of the Mcl-1 protein

Description

Serum

Reactivity

Human

Host

Rabbit

Epitope

AA 121-139

Vial size

0.1 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

References

Submitted references

Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse.

Kaufmann SH, Karp JE, Svingen PA, Krajewski S, Burke PJ, Gore SD, Reed JC
Blood 1998 Feb 1;91(3):991-1000

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Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.

Krajewski S, Bodrug S, Krajewska M, Shabaik A, Gascoyne R, Berean K, Reed JC
The American journal of pathology 1995 Jun;146(6):1309-19

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Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes.

Krajewski S, Bodrug S, Gascoyne R, Berean K, Krajewska M, Reed JC
The American journal of pathology 1994 Sep;145(3):515-25