Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- MA5-13929 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-MCL1 Monoclonal Antibody (RC13), Biotin
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-13937 targets von Hippel-Lindau Protein in IHC (P), ICC/IF and WB applications and shows reactivity with Human and mouse samples. The MA5-13937 immunogen is a recombinant protein containing aa 1-213 of human VHL.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- RC13
- Vial size
- 500 µL
- Concentration
- 0.4 mg/ml
- Storage
- 4° C
Submitted references Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.
Identification of novel target proteins in sebaceous gland carcinoma.
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.
Short nucleotide polymorphic insertions in the MCL-1 promoter affect gene expression.
Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
Stat3 activation in human endometrial and cervical cancers.
Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW
FEBS letters 2017 Jan;591(1):240-251
FEBS letters 2017 Jan;591(1):240-251
Identification of novel target proteins in sebaceous gland carcinoma.
Erovic BM, Al Habeeb A, Harris L, Goldstein DP, Kim D, Ghazarian D, Irish JC
Head & neck 2013 May;35(5):642-8
Head & neck 2013 May;35(5):642-8
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.
Campbell S, Hazes B, Kvansakul M, Colman P, Barry M
The Journal of biological chemistry 2010 Feb 12;285(7):4695-708
The Journal of biological chemistry 2010 Feb 12;285(7):4695-708
Short nucleotide polymorphic insertions in the MCL-1 promoter affect gene expression.
Saxena A, Moshynska OV, Moshynskyy ID, Neuls ED, Qureshi T, Bosch M, Voralia M, Bonham K
Cancer letters 2007 Jun 18;251(1):114-31
Cancer letters 2007 Jun 18;251(1):114-31
Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
Gomez-Bougie P, Wuillème-Toumi S, Ménoret E, Trichet V, Robillard N, Philippe M, Bataille R, Amiot M
Cancer research 2007 Jun 1;67(11):5418-24
Cancer research 2007 Jun 1;67(11):5418-24
Stat3 activation in human endometrial and cervical cancers.
Chen CL, Hsieh FC, Lieblein JC, Brown J, Chan C, Wallace JA, Cheng G, Hall BM, Lin J
British journal of cancer 2007 Feb 26;96(4):591-9
British journal of cancer 2007 Feb 26;96(4):591-9
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human tonsil stained with CD43 antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of T cells.
- Conjugate
- Biotin