HPA008455

antibody from Atlas Antibodies

Targeting: MCL1 BCL2L3, Mcl-1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA008455

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA008455, RRID:AB_1079334

Product name

Anti-MCL1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MCL1, Gene description: myeloid cell leukemia 1, Alternative Gene Names: BCL2L3, Mcl-1, Validated applications: WB, IHC, Uniprot ID: Q07820, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.4 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1

Wu X, Luo Q, Zhao P, Chang W, Wang Y, Shu T, Ding F, Li B, Liu Z
Cell Death & Differentiation 2019;27(1):55-70

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Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck

Carter R, Milani M, Butterworth M, Alotibi A, Harper N, Yedida G, Greaves G, Al-Zebeeby A, Jorgensen A, Schache A, Risk J, Shaw R, Jones T, Sacco J, Hurlstone A, Cohen G, Varadarajan S
Cell Death & Disease 2019;10(12)

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Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression

Márquez-Jurado S, Díaz-Colunga J, das Neves R, Martinez-Lorente A, Almazán F, Guantes R, Iborra F
Nature Communications 2018;9(1)

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SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production

Roders N, Herr F, Ambroise G, Thaunat O, Portier A, Vazquez A, Durrbach A
Frontiers in Immunology 2018;9

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IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

Ladanyi M, Li Y, Buijs-Gladdines J, Canté-Barrett K, Stubbs A, Vroegindeweij E, Smits W, van Marion R, Dinjens W, Horstmann M, Kuiper R, Buijsman R, Zaman G, van der Spek P, Pieters R, Meijerink J
PLOS Medicine 2016;13(12):e1002200

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Global variability in gene expression and alternative splicing is modulated by mitochondrial content

Guantes R, Rastrojo A, Neves R, Lima A, Aguado B, Iborra F
Genome Research 2015;25(5):633-644

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Global variability in gene expression and alternative splicing is modulated by mitochondrial content

Guantes R, Rastrojo A, Neves R, Lima A, Aguado B, Iborra F
Genome Research 2015 May;25(5):633-644

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Targeting Bcl-2/Bcl-XL Induces Antitumor Activity in Uveal Melanoma Patient-Derived Xenografts

Smalley K, Némati F, de Montrion C, Lang G, Kraus-Berthier L, Carita G, Sastre-Garau X, Berniard A, Vallerand D, Geneste O, de Plater L, Pierré A, Lockhart B, Desjardins L, Piperno-Neumann S, Depil S, Decaudin D
PLoS ONE 2014;9(1):e80836

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The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

Aries I, Hansen B, Koch T, van den Dungen R, Evans W, Pieters R, den Boer M
Haematologica 2013;98(12):1905-1911