ABIN966544

antibody from antibodies-online

Targeting: MCL1 BCL2L3, Mcl-1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966544

Provider

antibodies-online

Product name

anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody

Antibody type

Polyclonal

Antigen

Other

Reactivity

Human

Vial size

0.1 mg

References

Submitted references

Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis.

Piret JP, Minet E, Cosse JP, Ninane N, Debacq C, Raes M, Michiels C
The Journal of biological chemistry 2005 Mar 11;280(10):9336-44

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Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DC, Hinds MG
The Journal of biological chemistry 2005 Feb 11;280(6):4738-44

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Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

Nencioni A, Hua F, Dillon CP, Yokoo R, Scheiermann C, Cardone MH, Barbieri E, Rocco I, Garuti A, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A
Blood 2005 Apr 15;105(8):3255-62

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Antiapoptotic protein partners fortilin and MCL1 independently protect cells from 5-fluorouracil-induced cytotoxicity.

Graidist P, Phongdara A, Fujise K
The Journal of biological chemistry 2004 Sep 24;279(39):40868-75

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Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia.

Johnston JB, Paul JT, Neufeld NJ, Haney N, Kropp DM, Hu X, Cheang M, Gibson SB
Leukemia & lymphoma 2004 Oct;45(10):2017-27

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Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e.

Joo EK, Broxmeyer HE, Kwon HJ, Kang HB, Kim JS, Lim JS, Choe YK, Choe IS, Myung PK, Lee Y
Stem cells and development 2004 Oct;13(5):563-70

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

Herrant M, Jacquel A, Marchetti S, Belhacène N, Colosetti P, Luciano F, Auberger P
Oncogene 2004 Oct 14;23(47):7863-73

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VEGF induces Mcl-1 up-regulation and protects multiple myeloma cells against apoptosis.

Le Gouill S, Podar K, Amiot M, Hideshima T, Chauhan D, Ishitsuka K, Kumar S, Raje N, Richardson PG, Harousseau JL, Anderson KC
Blood 2004 Nov 1;104(9):2886-92

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Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

Michels J, O'Neill JW, Dallman CL, Mouzakiti A, Habens F, Brimmell M, Zhang KY, Craig RW, Marcusson EG, Johnson PW, Packham G
Oncogene 2004 Jun 17;23(28):4818-27

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Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.

Inoshita S, Takeda K, Hatai T, Terada Y, Sano M, Hata J, Umezawa A, Ichijo H
The Journal of biological chemistry 2002 Nov 15;277(46):43730-4