Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 51044-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#51044-1-AP, RRID:AB_2099137
- Product name
- ELL antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ELL antibody (Cat. #51044-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inherited blood cancer predisposition through altered transcription elongation.
Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity.
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival.
ELL targets c-Myc for proteasomal degradation and suppresses tumour growth.
ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cells.
Zhao J, Cato LD, Arora UP, Bao EL, Bryant SC, Williams N, Jia Y, Goldman SR, Nangalia J, Erb MA, Vos SM, Armstrong SA, Sankaran VG
Cell 2024 Feb 1;187(3):642-658.e19
Cell 2024 Feb 1;187(3):642-658.e19
Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity.
Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM
Nature communications 2018 Oct 23;9(1):4406
Nature communications 2018 Oct 23;9(1):4406
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia.
Wang H, Bei L, Shah CA, Huang W, Platanias LC, Eklund EA
Oncogene 2018 May;37(19):2532-2544
Oncogene 2018 May;37(19):2532-2544
Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival.
Alexander LMM, Watters J, Reusch JA, Maurin M, Nepon-Sixt BS, Vrzalikova K, Alexandrow MG, Murray PG, Wright KL
Molecular immunology 2017 Nov;91:8-16
Molecular immunology 2017 Nov;91:8-16
ELL targets c-Myc for proteasomal degradation and suppresses tumour growth.
Chen Y, Zhou C, Ji W, Mei Z, Hu B, Zhang W, Zhang D, Wang J, Liu X, Ouyang G, Zhou J, Xiao W
Nature communications 2016 Mar 24;7:11057
Nature communications 2016 Mar 24;7:11057
ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cells.
Liu L, Ai J, Xiao W, Liu J, Wang Y, Xin D, He Z, Guo Y, Wang Z
The Prostate 2010 May 15;70(7):797-805
The Prostate 2010 May 15;70(7):797-805
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 51044-1-AP(ELL antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ELL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ELL. This antibody recognizes human, mouse antigen. The ELL antibody has been validated for the following applications: ELISA, WB, IHC analysis.