66363-1-Ig

antibody from Proteintech Group

Targeting: CHRNA5

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66363-1-Ig

Provider

Proteintech Group

Product name

CHRNA5 antibody

Antibody type

Monoclonal

Description

CHRNA5 antibody (Cat. #66363-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3G8C11

Vial size

20ul, 150ul

References

Submitted references

PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.

Li Q, Li J, Wang J, Wang J, Lu T, Jia Y, Sun H, Ma X
Molecular carcinogenesis 2024 Feb;63(2):253-265

---

α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.

Kang G, Jiao Y, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Wang J, Sun H, Ma X
Carcinogenesis 2023 Dec 15;44(10-11):773-784

---

Acetylcholine promotes chronic stress-induced lung adenocarcinoma progression via α5-nAChR/FHIT pathway.

Jiao Y, Kang G, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Zhang L, Sun H, Ma X
Cellular and molecular life sciences : CMLS 2023 Apr 7;80(5):119

---

CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.

Wang J, Li X, Zhang P, Yang T, Liu N, Qin L, Ma G, Li X, Fan H, Huang S, Dang N
The Journal of investigative dermatology 2022 Nov;142(11):2978-2987.e6

---

α5-nAChR associated with Ly6E modulates cell migration via TGF-β1/Smad signaling in non-small cell lung cancer.

Zhang Q, Jia Y, Pan P, Zhang X, Jia Y, Zhu P, Chen X, Jiao Y, Kang G, Zhang L, Ma X
Carcinogenesis 2022 May 19;43(4):393-404

---

The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration.

Jia Y, Zhang Q, Liu Z, Pan P, Jia Y, Zhu P, Jiao Y, Kang G, Ma X
Toxicology 2022 Mar 15;469:153120

---

The α5-nAChR/PD-L1 axis facilitates lung adenocarcinoma cell migration and invasion.

Zhu P, Kang G, Jiao Y, Gui C, Fan H, Li X, Jia Y, Zhang L, Ma X
Human cell 2022 Jul;35(4):1207-1218

---

Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling.

Zhu P, Jin Z, Kang G, Jia Y, Liu D, Zhang Q, Guo F, Jia Y, Jiao Y, Li J, Sun H, Ma X
Cell communication and signaling : CCS 2022 Aug 15;20(1):121