Antibody data

Product number
BS60415 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GNAI1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human GNAI1.
Description
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Ï«, ÉÇ and ÎÛ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Ï« subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of GÏ« subunits have been identified; these include Gs, Gi, Gq and GÏ« 12/13. The Gi class comprises all the known Ï« subunits that are susceptible to pertussis toxin modifications, including GÏ« i-1, GÏ« i-2, GÏ« i-3, GÏ« o, GÏ« t1, GÏ« t2, GÏ« z and GÏ« gust. Of these, the three GÏ« i subtypes function to open atrial potassium channels.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GNAI1 protein structure - BS60415 shown in red.