Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- PA3-813 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- RAR gamma-1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA3-813 detects recombinant human retinoic acid receptor (RAR) gamma-1. The immunizing sequence is 100% conserved in mouse. This antibody detects RAR gamma-1, but not RAR gamma-2, or either of the alpha or beta forms of RAR. PA3-813 has been successfully used in Western blot, immunoprecipitation and gel shift procedures. By Western blot, this antibody detects an ~50 kDa protein representing RAR gamma-1 from transiently transfected 293T cells. PA3-813 has been shown to efficiently super shift the human RAR gamma-1/retinoid X receptor (RXR)/RAR response element complex in gel super shift experiments using a number of different response elements. PA3-813 immunizing peptide corresponds to the N-terminus of RAR gamma-1. This peptide (Cat. # PEP-228) is available for use in neutralization and control experiments.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- Conc. Not Determined
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Pharmacologic retinoid signaling and physiologic retinoic acid receptor signaling inhibit basal cell carcinoma tumorigenesis.
The expression of retinoic acid receptor alpha is increased in the granule cells of the dentate gyrus in schizophrenia.
So PL, Fujimoto MA, Epstein EH Jr
Molecular cancer therapeutics 2008 May;7(5):1275-84
Molecular cancer therapeutics 2008 May;7(5):1275-84
The expression of retinoic acid receptor alpha is increased in the granule cells of the dentate gyrus in schizophrenia.
Rioux L, Arnold SE
Psychiatry research 2005 Jan 30;133(1):13-21
Psychiatry research 2005 Jan 30;133(1):13-21
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