Explore
Validate
Learn66898-1-Ig
antibody from Proteintech Group
Targeting: UPF1
HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66898-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- UPF1 antibody
- Antibody type
- Monoclonal
- Description
- UPF1 antibody (Cat. #66898-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3B6B5
- Vial size
- 20ul, 150ul
Submitted references TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS.
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons.
Inhibiting UPF1 methylation enhances tumor immunotherapy sensitivity by reducing nonsense-mediated mRNA decay.
Widespread 3' UTR splicing regulates expression of oncogene transcripts through multiple mechanisms.
LINC00626 drives tamoxifen resistance in breast cancer cells by interaction with UPF1.
CircMAPK1 induces cell pyroptosis in sepsis-induced lung injury by mediating KDM2B mRNA decay to epigenetically regulate WNK1.
Prenatal diagnostic approaches diagnosed craniosynostosis and identified a novel nonsense variant in SMAD6 in a Chinese fetus.
Nonsense-mediated mRNA decay suppresses injury-induced muscle regeneration via inhibiting MyoD transcriptional activity.
O-GlcNAcylation promotes topoisomerase IIα catalytic activity in breast cancer chemoresistance.
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
Inhibition of Nonsense-Mediated Decay Induces Nociceptive Sensitization through Activation of the Integrated Stress Response.
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Alessandrini F, Wright M, Kurosaki T, Perloff OS, Ngo M, Kofler JK, Donnelly CJ, Maquat LE, Kiskinis E
Neuron 2026 Feb 18;114(4):640-660.e10
Neuron 2026 Feb 18;114(4):640-660.e10
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons.
Hölbling BV, Gupta Y, Marchi PM, Atilano ML, Flower M, Ureña E, Goulden RA, Dobbs HK, Katona E, Mikheenko A, Giblin A, Awan AR, Fisher-Ward CL, O'Brien N, Vaizoglu D, Kempthorne L, Wilson KM, Gittings LM, Carcolé M, Ruepp MD, Mizielinska S, Partridge L, Fratta P, Tabrizi SJ, Selvaraj BT, Chandran S, Armstrong E, Whiting P, Isaacs AM
Cell reports 2025 May 27;44(5):115695
Cell reports 2025 May 27;44(5):115695
Inhibiting UPF1 methylation enhances tumor immunotherapy sensitivity by reducing nonsense-mediated mRNA decay.
Zhu S, Bai Y, Zhang D, Huang C, Qian X, Li P, Xie T, Wu Q, Liu A, Zhu T, Yang W, She X, Li M, Rao Z, Chen S, Liu L, Yu C, Liu X, Wang G, Zhang G, Hu J
Cell reports 2025 Jul 22;44(7):115919
Cell reports 2025 Jul 22;44(7):115919
Widespread 3' UTR splicing regulates expression of oncogene transcripts through multiple mechanisms.
Riley JJ, Alexandru-Crivac CN, Bryce-Smith S, Wilson SA, Sudbery IM
Nucleic acids research 2025 Jul 19;53(14)
Nucleic acids research 2025 Jul 19;53(14)
LINC00626 drives tamoxifen resistance in breast cancer cells by interaction with UPF1.
Yuan H, Zhou L, Hu W, Yang M
Scientific reports 2025 Jan 23;15(1):2997
Scientific reports 2025 Jan 23;15(1):2997
CircMAPK1 induces cell pyroptosis in sepsis-induced lung injury by mediating KDM2B mRNA decay to epigenetically regulate WNK1.
Li M, Lu H, Ruan C, Ke Q, Hu L, Li Z, Liu X
Molecular medicine (Cambridge, Mass.) 2024 Sep 19;30(1):155
Molecular medicine (Cambridge, Mass.) 2024 Sep 19;30(1):155
Prenatal diagnostic approaches diagnosed craniosynostosis and identified a novel nonsense variant in SMAD6 in a Chinese fetus.
Hong Z, He X, Duan J, Yu F, Liu H, Lu D, Wang M, Zhang Y
Gene 2024 Feb 20;896:147994
Gene 2024 Feb 20;896:147994
Nonsense-mediated mRNA decay suppresses injury-induced muscle regeneration via inhibiting MyoD transcriptional activity.
Tan Y, Zhang J, Jin Y
Journal of cellular physiology 2023 Nov;238(11):2638-2650
Journal of cellular physiology 2023 Nov;238(11):2638-2650
O-GlcNAcylation promotes topoisomerase IIα catalytic activity in breast cancer chemoresistance.
Liu Y, Yu K, Zhang K, Niu M, Chen Q, Liu Y, Wang L, Zhang N, Li W, Zhong X, Li G, Wu S, Zhang J, Liu Y
EMBO reports 2023 Jul 5;24(7):e56458
EMBO reports 2023 Jul 5;24(7):e56458
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
Duan Z, Ma L, Jin J, Ma L, Ye L, Wu J, Luo Y
European journal of immunology 2023 Aug;53(8):e2250261
European journal of immunology 2023 Aug;53(8):e2250261
Inhibition of Nonsense-Mediated Decay Induces Nociceptive Sensitization through Activation of the Integrated Stress Response.
de la Peña JB, Chase R, Kunder N, Smith PR, Lou TF, Stanowick A, Suresh P, Shukla T, Butcher SE, Price TJ, Campbell ZT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Apr 19;43(16):2921-2933
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Apr 19;43(16):2921-2933
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1.
Wang X, Lai Q, He J, Li Q, Ding J, Lan Z, Gu C, Yan Q, Fang Y, Zhao X, Liu S
International journal of medical sciences 2019;16(1):51-59
International journal of medical sciences 2019;16(1):51-59
No comments: Submit comment
No validations: Submit validation data