Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15070-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15070-1-AP, RRID:AB_2236759
- Product name
- PCBP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PCBP2 antibody (Cat. #15070-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human brain small extracellular vesicles contain selectively packaged, full-length mRNA.
Unveiling poly(rC)-binding protein 2 as the target protein for curcusone C against prostate cancer: mechanism validation through click chemistry-activity based proteomics profiling approach.
Human hematopoietic stem cell vulnerability to ferroptosis.
N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71.
PCBP2 maintains antiviral signaling homeostasis by regulating cGAS enzymatic activity via antagonizing its condensation.
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
PCBP2 Posttranscriptional Modifications Induce Breast Cancer Progression via Upregulation of UFD1 and NT5E.
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3C(pro).
Cellular poly(C) binding protein 2 interacts with porcine epidemic diarrhea virus papain-like protease 1 and supports viral replication.
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Spatiotemporal Expression of Poly(rC)-Binding Protein PCBP2 Modulates Schwann Cell Proliferation After Sciatic Nerve Injury.
Ransom LS, Liu CS, Dunsmore E, Palmer CR, Nicodemus J, Ziomek D, Williams N, Chun J
Cell reports 2024 Apr 23;43(4):114061
Cell reports 2024 Apr 23;43(4):114061
Unveiling poly(rC)-binding protein 2 as the target protein for curcusone C against prostate cancer: mechanism validation through click chemistry-activity based proteomics profiling approach.
Huang L, Ma B, Zhang C, Shi J, Shen R, Zhang E, Lian C, Wang C, Liu J
BMC cancer 2023 Oct 9;23(1):957
BMC cancer 2023 Oct 9;23(1):957
Human hematopoietic stem cell vulnerability to ferroptosis.
Zhao J, Jia Y, Mahmut D, Deik AA, Jeanfavre S, Clish CB, Sankaran VG
Cell 2023 Feb 16;186(4):732-747.e16
Cell 2023 Feb 16;186(4):732-747.e16
N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71.
Hao H, Liu W, Miao Y, Ma L, Yu B, Liu L, Yang C, Zhang K, Chen Z, Yang J, Zheng Z, Zhang B, Deng F, Gong P, Yuan J, Hu Z, Guan W
Nucleic acids research 2022 Sep 9;50(16):9339-9354
Nucleic acids research 2022 Sep 9;50(16):9339-9354
PCBP2 maintains antiviral signaling homeostasis by regulating cGAS enzymatic activity via antagonizing its condensation.
Gu H, Yang J, Zhang J, Song Y, Zhang Y, Xu P, Zhu Y, Wang L, Zhang P, Li L, Chen D, Sun Q
Nature communications 2022 Mar 23;13(1):1564
Nature communications 2022 Mar 23;13(1):1564
METTL3 preferentially enhances non-m(6)A translation of epigenetic factors and promotes tumourigenesis.
Wei X, Huo Y, Pi J, Gao Y, Rao S, He M, Wei Q, Song P, Chen Y, Lu D, Song W, Liang J, Xu L, Wang H, Hong G, Guo Y, Si Y, Xu J, Wang X, Ma Y, Yu S, Zou D, Jin J, Wang F, Yu J
Nature cell biology 2022 Aug;24(8):1278-1290
Nature cell biology 2022 Aug;24(8):1278-1290
PCBP2 Posttranscriptional Modifications Induce Breast Cancer Progression via Upregulation of UFD1 and NT5E.
Wang X, Guo Q, Wang H, Yuan X, Wang B, Lobie PE, Zhu T, Tan S, Wu Z
Molecular cancer research : MCR 2021 Jan;19(1):86-98
Molecular cancer research : MCR 2021 Jan;19(1):86-98
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3C(pro).
Xiao H, Li J, Yang X, Li Z, Wang Y, Rui Y, Liu B, Zhang W
Virologica Sinica 2021 Dec;36(6):1363-1374
Virologica Sinica 2021 Dec;36(6):1363-1374
Cellular poly(C) binding protein 2 interacts with porcine epidemic diarrhea virus papain-like protease 1 and supports viral replication.
Zhang P, Yu L, Dong J, Liu Y, Zhang L, Liang P, Wang L, Chen B, Huang L, Song C
Veterinary microbiology 2020 Aug;247:108793
Veterinary microbiology 2020 Aug;247:108793
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Chen C, Lei J, Zheng Q, Tan S, Ding K, Yu C
FEBS open bio 2018 May;8(5):764-773
FEBS open bio 2018 May;8(5):764-773
Spatiotemporal Expression of Poly(rC)-Binding Protein PCBP2 Modulates Schwann Cell Proliferation After Sciatic Nerve Injury.
Chen Z, Zhang W, Ni L, Wang G, Cao Y, Wu W, Sun C, Yuan D, Ni H, Wang Y, Yang H
Cellular and molecular neurobiology 2016 Jul;36(5):725-35
Cellular and molecular neurobiology 2016 Jul;36(5):725-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15070-1-AP(PCBP2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PCBP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PCBP2. This antibody recognizes human,mouse,rat antigen. The PCBP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.