Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16190-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16190-1-AP, RRID:AB_2231751
- Product name
- FcRn-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FcRn-Specific antibody (Cat. #16190-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic Efficacy of YH35324 on FcεRIα-Mediated Mast Cell/Basophil Activation.
The neonatal Fc receptor (FcRn) is required for porcine reproductive and respiratory syndrome virus uncoating.
Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium.
Prevention of Hypercholesterolemia with "Liposomes in Microspheres" Composite Carriers: A Promising Approach for Intestinal-Targeted Oral Delivery of Astaxanthin.
Characterization of a primary cellular airway model for inhalative drug delivery in comparison with the established permanent cell lines CaLu3 and RPMI 2650.
Recombinant Humanized IgG1 Antibody Promotes Reverse Cholesterol Transport through FcRn-ERK1/2-PPARα Pathway in Hepatocytes.
Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs.
Human antibodies can cross guinea pig placenta and bind its neonatal Fc Receptor: implications for studying immune prophylaxis and therapy during pregnancy.
Ryu MS, Yang EM, Ye YM, Jang JH, Kim J, Lee SY, Park HS
Allergy, asthma & immunology research 2025 Mar;17(2):181-195
Allergy, asthma & immunology research 2025 Mar;17(2):181-195
The neonatal Fc receptor (FcRn) is required for porcine reproductive and respiratory syndrome virus uncoating.
Yang K, Dong J, Li J, Zhou R, Jia X, Sun Z, Zhang W, Li Z
Journal of virology 2025 Jan 31;99(1):e0121824
Journal of virology 2025 Jan 31;99(1):e0121824
Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium.
Togami K, Wolf W, Olson LC, Card M, Shen L, Schaefer A, Okuda K, Zeitlin L, Pauly M, Whaley K, Pickles RJ, Lai SK
Frontiers in immunology 2024;15:1371156
Frontiers in immunology 2024;15:1371156
Prevention of Hypercholesterolemia with "Liposomes in Microspheres" Composite Carriers: A Promising Approach for Intestinal-Targeted Oral Delivery of Astaxanthin.
Liu A, He M, Liu C, Ye Z, Tan CP, Liu Y, Gong J, Lei J, He Y, Zhu S, Zhao J, Xu YJ, Liu Y
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6118-6132
Journal of agricultural and food chemistry 2024 Mar 27;72(12):6118-6132
Characterization of a primary cellular airway model for inhalative drug delivery in comparison with the established permanent cell lines CaLu3 and RPMI 2650.
Martin J, Rittersberger R, Treitler S, Kopp P, Ibraimi A, Koslowski G, Sickinger M, Dabbars A, Schindowski K
In vitro models 2024 Dec;3(4-6):183-203
In vitro models 2024 Dec;3(4-6):183-203
Recombinant Humanized IgG1 Antibody Promotes Reverse Cholesterol Transport through FcRn-ERK1/2-PPARα Pathway in Hepatocytes.
Li Z, Zhang Q, Liu X, Zhao M
International journal of molecular sciences 2022 Nov 23;23(23)
International journal of molecular sciences 2022 Nov 23;23(23)
Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Zhao X, Zhang G, Liu S, Chen X, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi Y, Gao S, Shi Y, Yan J, Zhang Y, Xie Z, Wei W, Gao GF
Cell 2019 May 30;177(6):1553-1565.e16
Cell 2019 May 30;177(6):1553-1565.e16
Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs.
Xu Y, Ma L, Norton MG, Stuart C, Zhao Z, Toibero D, Dahlen S, Zhong L, Zhang P, Struble EB
Placenta 2015 Dec;36(12):1370-7
Placenta 2015 Dec;36(12):1370-7
Human antibodies can cross guinea pig placenta and bind its neonatal Fc Receptor: implications for studying immune prophylaxis and therapy during pregnancy.
Struble EB, Ma L, Zhong L, Lesher A, Beren J, Zhang P
Clinical & developmental immunology 2012;2012:538701
Clinical & developmental immunology 2012;2012:538701
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The FcRn-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human FcRn-Specific. This antibody recognizes human antigen. The FcRn-Specific antibody has been validated for the following applications: ELISA, WB analysis.