HPA012122

antibody from Atlas Antibodies

Targeting: FCGRT alpha-chain, FCRN

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA012122

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA012122, RRID:AB_1848474

Product name

Anti-FCGRT

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human FCGRT, Gene description: Fc fragment of IgG, receptor, transporter, alpha, Alternative Gene Names: alpha-chain, FCRN, Validated applications: IHC, WB, Uniprot ID: P55899, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Dynamics of intracellular neonatal Fc receptor-ligand interactions in primary macrophages using biophysical fluorescence techniques.

Pannek A, Houghton FJ, Verhagen AM, Dower SK, Hinde E, Gleeson PA
Molecular biology of the cell 2022 Jan 1;33(1):ar6

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FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity

Hubbard J, Pyzik M, Rath T, Kozicky L, Sand K, Gandhi A, Grevys A, Foss S, Menzies S, Glickman J, Fiebiger E, Roopenian D, Sandlie I, Andersen J, Sly L, Baker K, Blumberg R
Journal of Experimental Medicine 2020;217(10)

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Expression of FcRn receptor in placental tissue and its relationship with IgG levels in term and preterm newborns

Lozano N, Lozano A, Marini V, Saranz R, Blumberg R, Baker K, Agresta M, Ponzio M
American Journal of Reproductive Immunology 2018;80(3)

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Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells

Alberio T, Forlani G, Lualdi M, Tosi G, Accolla R, Fasano M
Journal of Translational Medicine 2018;16(1)

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Albumin-based nanoparticles as methylprednisolone carriers for targeted delivery towards the neonatal Fc receptor in glomerular podocytes

Wu L, Chen M, Mao H, Wang N, Zhang B, Zhao X, Qian J, Xing C
International Journal of Molecular Medicine 2017;39(4):851-860

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Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

Ko S, Pegu A, Rudicell R, Yang Z, Joyce M, Chen X, Wang K, Bao S, Kraemer T, Rath T, Zeng M, Schmidt S, Todd J, Penzak S, Saunders K, Nason M, Haase A, Rao S, Blumberg R, Mascola J, Nabel G
Nature 2014;514(7524):642-645

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Robust Expression of the Human Neonatal Fc Receptor in a Truncated Soluble Form and as a Full-Length Membrane-Bound Protein in Fusion with eGFP

Karnik S, Seijsing J, Lindborg M, Löfblom J, Uhlén M, Gräslund T
PLoS ONE 2013;8(11):e81350

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Neonatal Fc Receptor Expression in Dendritic Cells Mediates Protective Immunity against Colorectal Cancer

Baker K, Rath T, Flak M, Arthur J, Chen Z, Glickman J, Zlobec I, Karamitopoulou E, Stachler M, Odze R, Lencer W, Jobin C, Blumberg R
Immunity 2013;39(6):1095-1107