BS2546

antibody from Bioworld Technology, Inc

Targeting: RTEL1-TNFRSF6B

Immunocytochemistry

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: BS2546 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS2546, RRID:AB_1662077
Product name: DcR3 (G287) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 261-310 of Human DcR3.
Description: Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the ¡ùdeath domain,¡ì that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (death receptor 3), DR4, DR5 and DR6. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. Non-death domain-containing receptors, designated decoy receptor 1 (DcR1) or TRID, DcR2 and DcR3, associate with specific ligands and may play a role in cellular resistance to apoptotic stimuli.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

RTEL1-TNFRSF6B protein structure - BS2546 shown in red.