AMM01731G

antibody from Leading Biology
Targeting: SLC9A3R1 EBP50, NHERF, NHERF1
Provider product page for AMM01731G
Western blot
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
AMM01731G - Provider product page
Provider
Leading Biology
Product name
SLC9A3R1 / NHERF1 / EBP50 Antibody (clone EBP-10)
Antibody type
Monoclonal
Description
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
Reactivity
Human
Host
Mouse
Antibody clone number
EBP-10
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
SLC9A3R1 protein structure - AMM01731G shown in red.