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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350057 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350057, RRID:AB_10785217
- Product name
- anti-Amiloride Sensitive Sodium Channel Subunitalpha (SCNN1A, SCNEA,alpha-ENaC) (Extracellular Domain) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the extracellular domain of human amiloride sensitive sodium channel subunit alpha (SCNN1A, SCNEA, Alpha-ENaC) conjugated to an immunogenic carrier protein was used as the antigen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Extracellular Domain
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.
Novel mutations responsible for autosomal recessive multisystem pseudohypoaldosteronism and sequence variants in epithelial sodium channel alpha-, beta-, and gamma-subunit genes.
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.
Polymorphisms of amiloride-sensitive sodium channel subunits in five sporadic cases of pseudohypoaldosteronism: do they have pathologic potential?
Hormonal regulation and genomic organization of the human amiloride-sensitive epithelial sodium channel alpha subunit gene.
Structural organisation of the gene encoding the alpha-subunit of the human amiloride-sensitive epithelial sodium channel.
Cloning and functional studies of splice variants of the alpha-subunit of the amiloride-sensitive Na+ channel.
Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel.
The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.
McDonald FJ, Western AH, McNeil JD, Thomas BC, Olson DR, Snyder PM
American journal of physiology. Renal physiology 2002 Sep;283(3):F431-6
American journal of physiology. Renal physiology 2002 Sep;283(3):F431-6
Novel mutations responsible for autosomal recessive multisystem pseudohypoaldosteronism and sequence variants in epithelial sodium channel alpha-, beta-, and gamma-subunit genes.
Saxena A, Hanukoglu I, Saxena D, Thompson RJ, Gardiner RM, Hanukoglu A
The Journal of clinical endocrinology and metabolism 2002 Jul;87(7):3344-50
The Journal of clinical endocrinology and metabolism 2002 Jul;87(7):3344-50
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.
Snyder PM, Olson DR, Thomas BC
The Journal of biological chemistry 2002 Jan 4;277(1):5-8
The Journal of biological chemistry 2002 Jan 4;277(1):5-8
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.
Harvey KF, Dinudom A, Cook DI, Kumar S
The Journal of biological chemistry 2001 Mar 16;276(11):8597-601
The Journal of biological chemistry 2001 Mar 16;276(11):8597-601
Polymorphisms of amiloride-sensitive sodium channel subunits in five sporadic cases of pseudohypoaldosteronism: do they have pathologic potential?
Arai K, Zachman K, Shibasaki T, Chrousos GP
The Journal of clinical endocrinology and metabolism 1999 Jul;84(7):2434-7
The Journal of clinical endocrinology and metabolism 1999 Jul;84(7):2434-7
Hormonal regulation and genomic organization of the human amiloride-sensitive epithelial sodium channel alpha subunit gene.
Chow YH, Wang Y, Plumb J, O'Brodovich H, Hu J
Pediatric research 1999 Aug;46(2):208-14
Pediatric research 1999 Aug;46(2):208-14
Structural organisation of the gene encoding the alpha-subunit of the human amiloride-sensitive epithelial sodium channel.
Ludwig M, Bolkenius U, Wickert L, Marynen P, Bidlingmaier F
Human genetics 1998 May;102(5):576-81
Human genetics 1998 May;102(5):576-81
Cloning and functional studies of splice variants of the alpha-subunit of the amiloride-sensitive Na+ channel.
Tucker JK, Tamba K, Lee YJ, Shen LL, Warnock DG, Oh Y
The American journal of physiology 1998 Apr;274(4 Pt 1):C1081-9
The American journal of physiology 1998 Apr;274(4 Pt 1):C1081-9
Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel.
McDonald FJ, Snyder PM, McCray PB Jr, Welsh MJ
The American journal of physiology 1994 Jun;266(6 Pt 1):L728-34
The American journal of physiology 1994 Jun;266(6 Pt 1):L728-34
The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.
Voilley N, Lingueglia E, Champigny G, Mattéi MG, Waldmann R, Lazdunski M, Barbry P
Proceedings of the National Academy of Sciences of the United States of America 1994 Jan 4;91(1):247-51
Proceedings of the National Academy of Sciences of the United States of America 1994 Jan 4;91(1):247-51
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