Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN954780 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sphingomyelin Synthase 2 (SGMS2) (AA 336-365), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column followed by peptide Affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 336-365, C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase.
Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice.
Sphingomyelin synthase 2 is palmitoylated at the COOH-terminal tail, which is involved in its localization in plasma membranes.
The domain responsible for sphingomyelin synthase (SMS) activity.
An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis.
Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.
Ternes P, Brouwers JF, van den Dikkenberg J, Holthuis JC
Journal of lipid research 2009 Nov;50(11):2270-7
Journal of lipid research 2009 Nov;50(11):2270-7
Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice.
Liu J, Zhang H, Li Z, Hailemariam TK, Chakraborty M, Jiang K, Qiu D, Bui HH, Peake DA, Kuo MS, Wadgaonkar R, Cao G, Jiang XC
Arteriosclerosis, thrombosis, and vascular biology 2009 Jun;29(6):850-6
Arteriosclerosis, thrombosis, and vascular biology 2009 Jun;29(6):850-6
Sphingomyelin synthase 2 is palmitoylated at the COOH-terminal tail, which is involved in its localization in plasma membranes.
Tani M, Kuge O
Biochemical and biophysical research communications 2009 Apr 10;381(3):328-32
Biochemical and biophysical research communications 2009 Apr 10;381(3):328-32
The domain responsible for sphingomyelin synthase (SMS) activity.
Yeang C, Varshney S, Wang R, Zhang Y, Ye D, Jiang XC
Biochimica et biophysica acta 2008 Oct;1781(10):610-7
Biochimica et biophysica acta 2008 Oct;1781(10):610-7
An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis.
Wang W, Yang X, Tangchaiburana S, Ndeh R, Markham JE, Tsegaye Y, Dunn TM, Wang GL, Bellizzi M, Parsons JF, Morrissey D, Bravo JE, Lynch DV, Xiao S
The Plant cell 2008 Nov;20(11):3163-79
The Plant cell 2008 Nov;20(11):3163-79
Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.
Villani M, Subathra M, Im YB, Choi Y, Signorelli P, Del Poeta M, Luberto C
The Biochemical journal 2008 Aug 15;414(1):31-41
The Biochemical journal 2008 Aug 15;414(1):31-41
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Supportive validation
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- IHC
Supportive validation
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- Experimental details
- FACS