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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13543-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13543-1-AP, RRID:AB_2085513
- Product name
- CROT antibody
- Antibody type
- Polyclonal
- Description
- CROT antibody (Cat. #13543-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CROT overactivation within peroxisomes confers chemoresistance to non-small cell lung cancer by targeting fatty acid oxidation-Nrf2-ferroptosis resistance axis.
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation.
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells.
The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway.
Hua C, Zhang G, Yu W, Zhou J, Ru L, Xue G, Zheng L, Wang M, Wang Y, Yu D, Wang Q, Liu J, Wang R, Deng W, Tang R, Guo W
Pharmacological research 2025 Oct;220:107911
Pharmacological research 2025 Oct;220:107911
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Choi J, Smith DM, Lee YJ, Cai D, Hossain MJ, O'Connor TJ, Deme P, Haughey NJ, Scafidi S, Riddle RC, Wolfgang MJ
iScience 2024 Sep 20;27(9):110642
iScience 2024 Sep 20;27(9):110642
Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation.
Sanford JD, Franklin D, Grois GA, Jin A, Zhang Y
The Journal of biological chemistry 2023 Jul;299(7):104908
The Journal of biological chemistry 2023 Jul;299(7):104908
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells.
Hsu J, Fatuzzo N, Weng N, Michno W, Dong W, Kienle M, Dai Y, Pasca A, Abu-Remaileh M, Rasgon N, Bigio B, Nasca C, Khosla C
The Journal of biological chemistry 2023 Feb;299(2):102848
The Journal of biological chemistry 2023 Feb;299(2):102848
The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway.
Li X, Gao X, Yuan J, Wang F, Xu X, Wang C, Liu H, Guan W, Zhang J, Xu G
Frontiers in endocrinology 2022;13:950345
Frontiers in endocrinology 2022;13:950345
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13543-1-AP(CROT antibody) at dilution of 1:1500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 13543-1-AP(CROT antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CROT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CROT. This antibody recognizes human, mouse, rat antigen. The CROT antibody has been validated for the following applications: ELISA, WB, IHC analysis.
