Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 11994-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11994-1-AP, RRID:AB_2113725
- Product name
- Glutamate receptor 2 antibody
- Antibody type
- Polyclonal
- Description
- Glutamate receptor 2 antibody (Cat. #11994-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Long-term variable photoperiod exposure impairs the mPFC and induces anxiety and depression-like behavior in male wistar rats.
Profiling of Sexually Dimorphic Genes in Neural Cells to Identify Eif2s3y, Whose Overexpression Causes Autism-Like Behaviors in Male Mice.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b -/- Mice Contributes to Synaptic and Social Deficiency.
As a Histone Deacetylase Inhibitor, γ-Aminobutyric Acid Upregulates GluR2 Expression: An In Vitro and In Vivo Study.
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.
CAMK2-Dependent Signaling in Neurons Is Essential for Survival.
A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Ca2+ -permeable AMPA receptors associated with epileptogenesis of hypothalamic hamartoma.
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons.
Molecular mechanisms underlying activity-dependent AMPA receptor cycling in retinal ganglion cells.
mGluR and NMDAR activation internalize distinct populations of AMPARs.
Hou Y, Wang Y, Song S, Zuo Y, Zhang H, Bai C, Zhao H, Zhang T
Experimental neurology 2022 Jan;347:113908
Experimental neurology 2022 Jan;347:113908
Profiling of Sexually Dimorphic Genes in Neural Cells to Identify Eif2s3y, Whose Overexpression Causes Autism-Like Behaviors in Male Mice.
Zhang M, Zhou Y, Jiang Y, Lu Z, Xiao X, Ning J, Sun H, Zhang X, Luo H, Can D, Lu J, Xu H, Zhang YW
Frontiers in cell and developmental biology 2021;9:669798
Frontiers in cell and developmental biology 2021;9:669798
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Liu J, Liu L, Han YS, Yi J, Guo C, Zhao HQ, Ling J, Wang YH
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Journal of cellular and molecular medicine 2021 Aug;25(15):7342-7353
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.
Niu M, Zheng N, Wang Z, Gao Y, Luo X, Chen Z, Fu X, Wang Y, Wang T, Liu M, Yao T, Yao P, Meng J, Zhou Y, Ge Y, Wang Z, Ma Q, Xu H, Zhang YW
Frontiers in cell and developmental biology 2020;8:598622
Frontiers in cell and developmental biology 2020;8:598622
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Zhang J, Xiao B, Li CX, Wang Y
Neural regeneration research 2020 Jul;15(7):1308-1315
Neural regeneration research 2020 Jul;15(7):1308-1315
Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b -/- Mice Contributes to Synaptic and Social Deficiency.
Wang M, Liu X, Hou Y, Zhang H, Kang J, Wang F, Zhao Y, Chen J, Liu X, Wang Y, Wu S
Frontiers in cellular neuroscience 2019;13:447
Frontiers in cellular neuroscience 2019;13:447
As a Histone Deacetylase Inhibitor, γ-Aminobutyric Acid Upregulates GluR2 Expression: An In Vitro and In Vivo Study.
Xing A, Li X, Jiang C, Chen Y, Wu S, Zhang J, An L
Molecular nutrition & food research 2019 Sep;63(17):e1900001
Molecular nutrition & food research 2019 Sep;63(17):e1900001
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Zhang H, Tian X, Lu X, Xu D, Guo Y, Dong Z, Li Y, Ma Y, Chen C, Yang Y, Yang M, Yang Y, Liu F, Zhou R, He M, Xiao F, Wang X
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.
Maciąg F, Majewski Ł, Boguszewski PM, Gupta RK, Wasilewska I, Wojtaś B, Kuznicki J
Biochimica et biophysica acta. Molecular cell research 2019 Jul;1866(7):1137-1150
Biochimica et biophysica acta. Molecular cell research 2019 Jul;1866(7):1137-1150
CAMK2-Dependent Signaling in Neurons Is Essential for Survival.
Kool MJ, Proietti Onori M, Borgesius NZ, van de Bree JE, Elgersma-Hooisma M, Nio E, Bezstarosti K, Buitendijk GHS, Aghadavoud Jolfaei M, Demmers JAA, Elgersma Y, van Woerden GM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 10;39(28):5424-5439
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 10;39(28):5424-5439
A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.
Capauto D, Colantoni A, Lu L, Santini T, Peruzzi G, Biscarini S, Morlando M, Shneider NA, Caffarelli E, Laneve P, Bozzoni I
Molecular neurobiology 2018 Oct;55(10):7635-7651
Molecular neurobiology 2018 Oct;55(10):7635-7651
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, Wang W, He M, Zhou R, Ma Y, Xu D, Tian X, Gao X, Wang Q, Wang X
Cell death & disease 2018 Jul 23;9(8):795
Cell death & disease 2018 Jul 23;9(8):795
Ca2+ -permeable AMPA receptors associated with epileptogenesis of hypothalamic hamartoma.
Kitaura H, Sonoda M, Teramoto S, Shirozu H, Shimizu H, Kimura T, Masuda H, Ito Y, Takahashi H, Kwak S, Kameyama S, Kakita A
Epilepsia 2017 Apr;58(4):e59-e63
Epilepsia 2017 Apr;58(4):e59-e63
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model.
Tang L, Zhang Y, Chen G, Xiong Y, Wang X, Zhu B
Neurochemical research 2017 Apr;42(4):1211-1218
Neurochemical research 2017 Apr;42(4):1211-1218
AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons.
Gruszczynska-Biegala J, Sladowska M, Kuznicki J
Frontiers in cellular neuroscience 2016;10:251
Frontiers in cellular neuroscience 2016;10:251
Molecular mechanisms underlying activity-dependent AMPA receptor cycling in retinal ganglion cells.
Casimiro TM, Nawy S, Carroll RC
Molecular and cellular neurosciences 2013 Sep;56:384-92
Molecular and cellular neurosciences 2013 Sep;56:384-92
mGluR and NMDAR activation internalize distinct populations of AMPARs.
Casimiro TM, Sossa KG, Uzunova G, Beattie JB, Marsden KC, Carroll RC
Molecular and cellular neurosciences 2011 Oct;48(2):161-70
Molecular and cellular neurosciences 2011 Oct;48(2):161-70
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11994-1-AP(GRIA2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 11994-1-AP(GRIA2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Glutamate receptor 2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Glutamate receptor 2. This antibody recognizes human,mouse,rat antigen. The Glutamate receptor 2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.