BS5724

antibody from Bioworld Technology, Inc
Targeting: FSHR FSHRO, LGR1, ODG1
Provider product page for BS5724
Western blot
Immunohistochemistry

Antibody data

Product number
BS5724 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FSHR polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 330-375 of Human FSHR.
Description
Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G-protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its Ï« and ÉÇ subunits. While the Ï« subunit of FSH is involved in the binding of FSH to the receptor, the ÉÇ subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FSHR protein structure - BS5724 shown in red.