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- Antibody Data
- Antigen structure
- References [28]
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- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 13560-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13560-1-AP, RRID:AB_2067220
- Product name
- BST2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BST2 antibody (Cat. #13560-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.
Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef.
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics.
IFNα-induced BST2(+) tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling.
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists.
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury.
Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinoma.
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
Identification of BST2 Contributing to the Development of Glioblastoma Based on Bioinformatics Analysis.
BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5' UTR.
Catch Me if You Can: the Crosstalk of Zika Virus and the Restriction Factor Tetherin.
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction.
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion.
Differential interferon pathway gene expression patterns in Rhabdomyosarcoma cells during Enterovirus 71 or Coxsackievirus A16 infection.
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.
BST2/Tetherin inhibits hepatitis C virus production in human hepatoma cells.
BST2/tetherin inhibits dengue virus release from human hepatoma cells.
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Li Q, Wen W, Wang Y, Gong T, Wang X, Tan Q, Fan B, Xie H, Li Y, Li S, Yang C, Zhou Z, Duan X, Lin W, Chen L
Journal of medical virology 2024 May;96(5):e29659
Journal of medical virology 2024 May;96(5):e29659
Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef.
Prelli Bozzo C, Laliberté A, De Luna A, Pastorio C, Regensburger K, Krebs S, Graf A, Blum H, Volcic M, Sparrer KMJ, Kirchhoff F
Nature communications 2024 May 7;15(1):3813
Nature communications 2024 May 7;15(1):3813
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
Jiang L, Wang S, Xia X, Zhang T, Wang X, Zeng F, Ma J, Fang X
Biochemical genetics 2024 Mar 5;
Biochemical genetics 2024 Mar 5;
Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics.
Říhová K, Lapčík P, Veselá B, Knopfová L, Potěšil D, Pokludová J, Šmarda J, Matalová E, Bouchal P, Beneš P
Journal of proteome research 2024 Aug 2;23(8):2999-3011
Journal of proteome research 2024 Aug 2;23(8):2999-3011
IFNα-induced BST2(+) tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling.
Zheng C, Wang J, Zhou Y, Duan Y, Zheng R, Xie Y, Wei X, Wu J, Shen H, Ye M, Kong B, Liu Y, Xu P, Zhang Q, Liang T
Cell reports 2024 Apr 23;43(4):114088
Cell reports 2024 Apr 23;43(4):114088
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
McDougal MB, De Maria AM, Ohlson MB, Kumar A, Xing C, Schoggins JW
EMBO reports 2023 Sep 6;24(9):e56901
EMBO reports 2023 Sep 6;24(9):e56901
Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists.
Hagelauer E, Lotke R, Kmiec D, Hu D, Hohner M, Stopper S, Nchioua R, Kirchhoff F, Sauter D, Schindler M
Viruses 2023 Nov 30;15(12)
Viruses 2023 Nov 30;15(12)
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
Cheng J, Zhang G, Deng T, Liu Z, Zhang M, Zhang P, Adeshakin FO, Niu X, Yan D, Wan X, Yu G
Cell death & disease 2023 May 20;14(5):333
Cell death & disease 2023 May 20;14(5):333
GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury.
Xie M, Xie R, Huang P, Yap DYH, Wu P
International journal of molecular sciences 2023 Jul 11;24(14)
International journal of molecular sciences 2023 Jul 11;24(14)
Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinoma.
Zou DD, Sun YZ, Li XJ, Wu WJ, Xu D, He YT, Qi J, Tu Y, Tang Y, Tu YH, Wang XL, Li X, Lu FY, Huang L, Long H, He L, Li X
eLife 2023 Dec 15;12
eLife 2023 Dec 15;12
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
Shan F, Shen S, Wang X, Chen G
International journal of oncology 2023 Apr;62(4)
International journal of oncology 2023 Apr;62(4)
Identification of BST2 Contributing to the Development of Glioblastoma Based on Bioinformatics Analysis.
Kong Y, Xue Z, Wang H, Cui G, Chen A, Liu J, Wang J, Li X, Huang B
Frontiers in genetics 2022;13:890174
Frontiers in genetics 2022;13:890174
BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5' UTR.
Zhao Y, Du J, Wang Y, Wang Q, Wang S, Zhao K
Journal of virology 2022 Jan 26;96(2):e0161021
Journal of virology 2022 Jan 26;96(2):e0161021
Catch Me if You Can: the Crosstalk of Zika Virus and the Restriction Factor Tetherin.
Herrlein ML, Schmanke P, Elgner F, Sabino C, Akhras S, Bender D, Glitscher M, Tabari D, Scholl C, Stingl J, Hildt E
Journal of virology 2022 Feb 23;96(4):e0211721
Journal of virology 2022 Feb 23;96(4):e0211721
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Gao W, Rui Y, Li G, Zhai C, Su J, Liu H, Zheng W, Zheng B, Zhang W, Yang Y, Hua S, Yu X
Frontiers in immunology 2021;12:740713
Frontiers in immunology 2021;12:740713
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Presle A, Frémont S, Salles A, Commere PH, Sassoon N, Berlioz-Torrent C, Gupta-Rossi N, Echard A
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Current biology : CB 2021 May 24;31(10):2203-2213.e5
ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction.
Zheng B, Zhang J, Zheng T, Wang H, Li Z, Huan C, Ning S, Wang Y, Zhang W
Journal of medical virology 2020 Feb;92(2):201-209
Journal of medical virology 2020 Feb;92(2):201-209
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Liu W, Li Y, Feng S, Guan Y, Cao Y
Journal of biochemistry 2020 Aug 1;168(2):159-170
Journal of biochemistry 2020 Aug 1;168(2):159-170
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.
Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge SF, Marx PA, Apetrei C, Kirchhoff F, Sauter D
Journal of virology 2018 Sep 15;92(18)
Journal of virology 2018 Sep 15;92(18)
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Liu W, Cao Y, Guan Y, Zheng C
Biotechnology letters 2018 Jul;40(7):1015-1027
Biotechnology letters 2018 Jul;40(7):1015-1027
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
Fu Y, Zhang L, Zhang F, Tang T, Zhou Q, Feng C, Jin Y, Wu Z
PLoS pathogens 2017 Sep;13(9):e1006611
PLoS pathogens 2017 Sep;13(9):e1006611
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Jin S, Tian S, Luo M, Xie W, Liu T, Duan T, Wu Y, Cui J
Molecular cell 2017 Oct 19;68(2):308-322.e4
Molecular cell 2017 Oct 19;68(2):308-322.e4
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion.
Yan R, Zhao X, Cai D, Liu Y, Block TM, Guo JT, Guo H
Journal of virology 2015 Sep;89(18):9200-12
Journal of virology 2015 Sep;89(18):9200-12
Differential interferon pathway gene expression patterns in Rhabdomyosarcoma cells during Enterovirus 71 or Coxsackievirus A16 infection.
Zhang W, Zhang L, Wu Z, Tien P
Biochemical and biophysical research communications 2014 May 9;447(3):550-5
Biochemical and biophysical research communications 2014 May 9;447(3):550-5
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.
Zhao X, Guo F, Liu F, Cuconati A, Chang J, Block TM, Guo JT
Proceedings of the National Academy of Sciences of the United States of America 2014 May 6;111(18):6756-61
Proceedings of the National Academy of Sciences of the United States of America 2014 May 6;111(18):6756-61
BST2/Tetherin inhibits hepatitis C virus production in human hepatoma cells.
Pan XB, Qu XW, Jiang D, Zhao XL, Han JC, Wei L
Antiviral research 2013 Apr;98(1):54-60
Antiviral research 2013 Apr;98(1):54-60
BST2/tetherin inhibits dengue virus release from human hepatoma cells.
Pan XB, Han JC, Cong X, Wei L
PloS one 2012;7(12):e51033
PloS one 2012;7(12):e51033
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Weidner JM, Jiang D, Pan XB, Chang J, Block TM, Guo JT
Journal of virology 2010 Dec;84(24):12646-57
Journal of virology 2010 Dec;84(24):12646-57
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 13560-1-AP(BST2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 13560-1-AP(BST2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 13560-1-AP(BST2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BST2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BST2. This antibody recognizes human antigen. The BST2 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
